Journal Information
Vol. 17. Issue 1.
Pages 38-40 (January - February 1981)
Share
Share
Download PDF
More article options
Vol. 17. Issue 1.
Pages 38-40 (January - February 1981)
Full text access
Alveolitis fibrosante con anemia hemolitica autoinmune
Fibrosing alveolitis with autoimmune hemolytic anemia
Visits
4429
M. Palomar Buil, E. Lopez-Bermejo Muñoz, M. Vaquer Albons, A. Ladaria Ferrer, E. De la Calle del Moral
Complejo Sanitario de la Seguridad Social «Virgen de Lluch». Departamento de Medicina Interna. Sección de Respiratorio. Palma de Mallorca
This item has received
Article information
Abstract
Bibliography
Download PDF
Statistics
Resumen

Se presenta el caso clínico de un paciente que radiográficamente tenía un patrón intersticial difuso. La anatomía patológica de estas alteraciones fue informada como alveolitis fibrosante. Además el enfermo tenía una anemia hemolítica autoinmune. Esta asociación ha sido referida únicamente en dos ocasiones anteriormente. Las alveolitis fíbrosantes se inician en ocasiones por el depósito de complejos inmunes en las membranas de los alvéolos, cosa que no ocurriría en la anemia hemolítica, ya que los complejos inmunes circulantes no se formarían. En los comentarios del caso clínico se exponen los posibles mecanismos que se han señalado en la literatura mundial para explicar las alteraciones a nivel pulmonar.

Summary

The authors present the clinical case of a patient whose X-ray showed a diffuse interstitial pattern. The pathological anatomy of these alterations were reported as fibrosing alveolitis. The patient also had an autoimmune hemolytic anemia. This association has been described in only two previous occasions. Fibrosing alveolitis are begun at times by the depositing of immune complexes in the membranes of the aveoli, a circumstance which would not happen in hemolytic anemia as the circulating immune complexes would not be formed. In the commentaries on this clinical case the authors describe the possible mechanisms that have been indicated in world literature in order to explain the pulmonary alterations.

Full text is only aviable in PDF
Bibliografia
[1.]
J.G. Scadding.
Diffuse pulmonary alveolar fibrosis.
Thorax, 29 (1974), pp. 271
[2.]
M. Turner-Warwick.
Immunological aspects of systemic diseases of the lungs.
Proc. Roy. Soc. Med., 67 (1974), pp. 541
[3.]
J.W. Scadding.
Fibrosing alveolitis with autoimmune haemolytic Anaemia: Two case reports.
Thorax, 32 (1977), pp. 134
[4.]
M. Turner-Warwick.
Cryptogenic fibrosing alveolitis.
Brit. J. Hosp. Med., 7 (1972), pp. 697
[5.]
J.M. Gumpel.
Sjögren's syndrome with pulmonary fibrosis. Waldenströrn's hyperglobulinaemic purpura and immune paresis.
Proc. Roy. Soc. Med., 64 (1971), pp. 397
[6.]
A.F. Lobuglio, R.S. Cotran, J.H. Jandl.
Red cells coated with immunoglobulin G: binding and sphering gy mononuclear cells in man.
Science, 158 (1967), pp. 1582
[7.]
J.V. Dacie, S.M. Worlledge.
Clinical Aspects of Immunology.
Ed. Balckwell, (1975), pp. 1.149
[8.]
M.O. Pinkett, C.R. Cowdrey, P.C. Nowell.
Mixed hematopoietic and pulmonary origin of «alveolar macrophages» as demonstrated by chromosome markers.
Am. J. Pathol., 48 (1966), pp. 859
[9.]
D.H. Bowden, I.Y.R. Adamson, W.G. Grantham, J.P. Wyatt.
Origin of the lung macrophage: evidence derived from radiation injury.
Arch. Pathol., 88 (1969), pp. 540
[10.]
G.P. Velo, W.G. Spector.
The origin and turnover of alveolar macrophages in experimental pneumonia.
J. Pathol., 109 (1973), pp. 7
[11.]
H. Spencer.
Pathology of the lung.
Ed. Pergamon Press, (1968), pp. 38
Copyright © 1981. Sociedad Española de Neumología y Cirugía Torácica
Archivos de Bronconeumología
Article options
Tools

Are you a health professional able to prescribe or dispense drugs?