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Vol. 18. Issue 4.
Pages 200-205 (July - August 1982)
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Vol. 18. Issue 4.
Pages 200-205 (July - August 1982)
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Intercambios gaseosos en la asbestosis pulmonar
Alterations in gas exchange in asbestosis
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V. Sobradillo Peña, J.I. Villate Navarro, M. Lasso Manzano, A. Diaz Pedreira
Sección de Respiratorio. Ciudad Sanitaria de la Seguridad Social «Enrique Sotomayor». Bilbao
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Resumen

Se presenta el estudio de los intercambios gaseosos, en reposo y al ejercicio en 14 pacientes con asbestosis pulmonar. La alteración de los intercambios gaseosos está en relación con la gravedad de la afectación radiológica. Los pacientes con alteraciones radiológicas más importantes presentan en reposo una hiperventilación con disminución de la eficacia respiratoria. La insuficiencia respiratoria en reposo no es frecuente. El ejercicio hace aparecer con más claridad las alteraciones de los intercambios gaseosos. La hiperventilación, el aumento del gradiente alveoloarterial de 02 y la desaturación al ejercicio, se observan en ocho de los nueve pacientes radiológicamente más afectados. Se discuten las causas fisiopatológicas que pueden explicar estos hechos.

Summary

The results of a study measuring gas exchange functions at rest and during exercise in a group of 14 patients with asbestosis are presented. The alterations in gas exchange function were related to the degree of affectation seen on x-ray. The patients in whom the x-ray showed the severest alterations also presented hyperventilation and impaired respiratory capacity while at rest. Respiratory insufficiency while at rest was but infraquently seen. The alterations in gas exchange function can be determined most obviously during exercise. Hyperventilation, increased alveolararterial gradients of O2 and desaturation during exercise were seen in 8 out of the 9 patients with severe radiological alterations. A discussion of the possible physiological causes for these findings is inclüded.

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Bibliografia
[1.]
M.R. Becklakes.
Pneumoconiosis.
Willians, Wilkins CO, (1964), pp. 1.601
[2.]
G.L. Leathart.
Pulmonary function test in asbestos workers.
Trans Sec Occup Med, 18 (1968), pp. 49
[3.]
D.V. Bates, P.T. Macklem, R.A. Christie.
Respiratory function in disease.
2 nd, WB Saunders, (1971),
[4.]
ILO., V/C.
International Classification of radiographe of Pneumoconiosis.
(1972),
[5.]
C.A. Soutar, G. Simon, M. Turner-Warwick.
The radiology of asbestos disease of the lung.
Br Dis Chest, 68 (1974), pp. 235
[6.]
C.A. Cara, L. Martin.
Etablisement des normes physiologiques en exploratorion fonctionelle pulmonaire, pp. 97
[7.]
P.H. Rossier, A. Burlmann, K. Wiesinger.
Physiologie et Physiopathologie de la respiration (Delachaux et Niestl édit.).
Neuchatel, (1958), pp. p471
[8.]
J. Lacoste, Y. Rouch, A. Rizzo.
Coefficiente de ductance pulmonaire por CO2 O2 et CO (homme sain et malade en repos).
Bull Physic Ptah Resp, 2 (1966), pp. 523
[9.]
N.E. Bader, R.A. Bader, I.J. Selikoff.
Pulmonary function in Asbestosis of the lung. An alveolar-capillary block Sybdrome.
Am J Med, 30 (1961), pp. 325
[10.]
J. Bjüre, B. Soderholm, J. Widimsky.
Cardiopulmonary function studies in workers with asbesto and glasswool.
Thorax, 19 (1964), pp. 22
[11.]
M. Pellet, R. Chevalier.
Physiopathologie respiratoire de l’asbestose pulmonaire.
Journal Med Lyon, 45 (1964), pp. 1.611
[12.]
G.L. Leathart.
The effect of asbestosis on pulmonary function.
The Newcastle Med J, 29 (1965), pp. 12
[13.]
E. Weitzemblum, C. Hirt, E.L. Charbi, Parini, P. Cudent.
Troubles des echanges gaseux dans les fibrosis intersticielles diffuses et dans d’autres pneumopathies intersticielles.
Rev Franc Mal Resp, 2 (1974), pp. 832
[14.]
J.B. West.
Ventilation-Perfusion relationships.
Am Rev Respir Dis, 116 (1977), pp. 919
[15.]
M. Barrocas, C.V. Nuchprayoon, N. Claudio, F.N. King, S. Danon, S.T. Shamp.
Gas exchange anormalities in diffuse lung disease.
Amer Rev Resp Dis, 104 (1971), pp. 72
[16.]
T.N. Finley, E.W. Swenson, J.N. Comroe.
The causes of arterial hypoxemia at rest in patients with alveolar-capillary block-syndrome.
J Clin Invest, 14 (1962), pp. 618
[17.]
J. Read, R. William.
Pulmonary ventilation, blood flow relationship in interstitial disease of the lung.
Amer J Med, 27 (1959), pp. 545
[18.]
D. Seaton.
Regional lung function in asbestos workers.
Thorac, 32 (1977), pp. 40
[19.]
K. Wasserman, B.I. Whipp.
Exercise physiologic in health and disease.
Am Rev Respir Dis, 112 (1975), pp. 219
[20.]
C. Gernez-Rieux, E. Balgairies, C. Clayes.
Consideracions sur les troubles respiratoires dans l’asbestose.
J. Francais Med et Chir Thorax, 8 (1954), pp. 193
[21.]
T. Sessa, C. Vechione, R. Mole, N. Javicoli.
Hypoxémie et équilibre acide-base chez les asbestosiques.
Poumen et Coeur, 30 (1974), pp. 135
[22.]
J.J. Woitowitz.
Die Bedentung des Asbesto für die ARbertsmedizin und Onkologie.
Deutsche Medizin Wochensch, 97 (1972), pp. 346
[23.]
R. Cohen, E.M. Overfield.
The diffusion component of arterial hypoxemie.
Amer Rev Resp Dis, 105 (1972), pp. 532
[24.]
W.R. Parkes.
Diseases due to asbestos and other silicates, en «occupational lung disorders».
Butterworth y Co. Ltd, (1974), pp. 270
Copyright © 1982. Sociedad Española de Neumología y Cirugía Torácica
Archivos de Bronconeumología

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