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Vol. 21. Issue 4.
Pages 160-166 (July - August 1985)
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Vol. 21. Issue 4.
Pages 160-166 (July - August 1985)
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Determinacion del volumen de tejido y flujo pulmonar por reinhalacion con espectrometria de masas
Determination of pulmonary tissue volume and blood flow by rebreathing with mass spectrometry
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N. Gonzalez Mangado, J.A. Barbera I mir, J. Vallejo Galbete, F. Lahoz Navarro
Sección de Fisiopatología Respiratoria. Servicio de Neumología. Fundación Jiménez Díaz. Clínica de Ntra. Sra. de la Concepción. Madrid
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Se efectuó la medición, con la técnica de reinhalación y medición por espirometría de masas, del volumen de tejido (Vt) y flujo pulmonar en cuatro sujetos, a los cuales se les efectuaron las pruebas en diferentes condiciones y con gases distintos (C2H2; DME y CO18). Se valoraron con cuatro métodos y a diferentes intervalos. Se usó material europeo de bajo coste, para el que se describen algunas adaptaciones. Los autores encuentran coeficientes de varianza para el Vt similar a otros autores con los métodos habituales, sin notar influencias importantes derivadas del nivel de ventilación, pero influidos por el nivel del volumen alveolar al que se inicia la prueba. Los valores con el DME eran discretamente más bajos que los del C2H2.

Se demuestra una marcada correlación entre los flujos pulmonares medidos con cualquier método y el nivel de frecuencia o ventilación al que se efectuó la prueba.

Se recomienda para futuros estudios el método de Petrini et al., tanto por su más fácil cálculo, como por permitir el efectuarse a más baja frecuencia.

Tissue volume (Vt) and pulmonary flow were determined using rebreathing and mass spirometry in four individuals who were tested under different conditions and with different gasses (C2H2; DME and CO18). Evaluations were done with four methods and at different intervals. Low cost european material was used and adapted. Results are in agreement with those of other authors using conventional Vt measurement methods without the ventilation level influencing results althoug alveolar volume at the start of the test did influence findings. DME values were slightly lower that C2H2 values.

There was marked correlation between pulmonary flow measured with different methods and the level of frequency or ventilation at which determinations were done. Petrini et al.’s method is recommended for studies of this type, both because its easier to calculate and can be done at lower frequency.

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Copyright © 1985. Sociedad Española de Neumología y Cirugía Torácica
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