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Vol. 21. Issue 5.
Pages 241-244 (September - October 1985)
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Vol. 21. Issue 5.
Pages 241-244 (September - October 1985)
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Efecto broncodilatador de los antiinflamatorios no esteroideos en el asma. Comunicacion de un caso
Bronchodilating effect of non-steroid anti-inflammatories in asthma. One case
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F. Sanchez-Toril, L. Prieto, J. Palop, M. Juyol, A. Paricio, J. Castro
Sección de Alergia. Servicio de Medicina Interna. Hospital Dr. Peset. Valencia
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Se describe un caso de rinosinusitis hiperplásica y asma bronquial intrínseco en el que diferentes analgésicos (dipirona, paracetamol, aspirina, indometacina, naproxen) mostraron efecto broncodilatador, que se objetivó mediante valoración funcional respiratoria antes y en diferentes momentos después de administrar cada fármaco. Es éste el 9.° enfermo comunicado hasta la actualidad con esta especial susceptibilidad a la acción de los analgésicos en sus vías aéreas y el primero en el que se ha objetivado la existencia de poliposis nasal y efecto broncodilatador con el paracetamol. Algunos de los rasgos clínicos encontrados en la paciente apoyan la hipótesis de que el efecto beneficioso de los analgésicos pudiera ser transitorio y que estos fármacos desencadenarían broncospasmo en un momento dado.

The authors describe a patient with hyperplasic rhino-sinusitis and intrinsic bronchial asthma with whom difierent analgesics (dipirone, paracetamol, aspirine, indo-methacin, naproxen) had a bronchodilating effect demonstrated through respiratory function tests before and at different moments following administration of each drug. To the authors knowledge this is only the 9th case documented with this particular susceptibility of the airways to these anaigesics and the first case with nasal polyposis and a bronchodilating effect of paracetamol.

Some of the clinical features of this patient support the hypothesis that the beneficial effect of these analgesics may be only transient and that the drugs will trigger bronchospasms at certain moments.

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Copyright © 1985. Sociedad Española de Neumología y Cirugía Torácica
Archivos de Bronconeumología
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