Síndrome de Stevens-Johnson asociado a neumonía atípica

Modesto Alapont, M.; Reyes Calzada, S.; Calabuig Muñoz, E.; Nauffal Manzur, D.

doi:10.1016/S0300-2896(03)75407-6

Archivos de Bronconeumología

ISSN: 0300-2896

Archivos de Bronconeumologia is an international journal that publishes original studies whose content is based upon results of research initiatives dealing with several aspects of respiratory medicine including epidemiology, respiratory physiology, pathophysiology of respiratory diseases, clinical management, thoracic surgery, pediatric lung diseases, respiratory critical care, respiratory allergy and translational research. Other types of articles such as editorials, reviews, and different types of letters are also published in the journal. Additionally, the journal expresses the voice of the following scientific societies: the Spanish Respiratory Society of Pneumology and Thoracic Surgery (SEPAR; https://www.separ.es/), the Latin American Thoracic Society (ALAT; https://alatorax.org/), and the Iberian American Association of Thoracic Surgery (AIACT; http://www.aiatorax.com/).

It is a monthly journal in which all manuscripts are sent to peer-review and handled by the editor or an associate editor from the team and the final decision is made on the basis of the comments from the expert reviewers and the editors. The journal is published solely in English. All the published data is composed of novel manuscripts not previously published in any other journal and not being in consideration for publication in any other journal..

The journal is indexed at Science Citation Index Expanded, Medline/Pubmed, Embase and SCOPUS. Access to any published article is possible through the journal's web page as well as from Pubmed, ScienceDirect, and other international databases. Furthermore, the journal is also present in X, Facebook and Linkedin. Manuscripts can be submitted electronically using the following web site: https://www.editorialmanager.com/ARBR/.

Indexed in:

Medline, Science Citation Index Expanded (SCIE)

El síndrome de Stevens-Johnson se caracteriza por un exantema generalizado asociado a fiebre alta, síntomas catarrales y mucositis. Ha sido relacionado con varias etiologías, entre las que destacan numerosos fármacos y algunos agentes productores de neumonías atípicas, y puede llegar a ser mortal hasta en el 5% de las ocasiones

Presentamos el caso de una paciente joven con una neumonía atípica bilateral que se acompañó de un exantema generalizado muy importante y requirió ingreso en la Unidad de Grandes Quemados de nuestro hospital. Fue diagnosticada de síndrome de Stevens-Johnson tras neumonía atípica por Mycoplasma pneumoniae con confirmación microbiológica y anatomopatológica

Palabras clave:

Neumonía atípica

Síndrome de Stevens-Johnson

Mycoplasma pneumoniae

Stevens-Johnson syndrome is characterized by generalized exanthema associated with high fever, catarrhal symptoms and mucositis. Various etiologies have been implicated, particularly numerous medications and certain agents of atypical pneumonia. Stevens-Johnson syndrome leads to death in up to 5% of cases

We describe the case of a 30-year-old woman with bilateral atypical pneumonia accompanied by severe generalized exanthema that required hospitalization in the serious burns unit of our hospital. She was diagnosed with Stevens-Johnson syndrome following atypical pneumonia caused by Mycoplasma pneumoniae with microbiological and pathological confirmation

Key words:

Atypical pneumonia

Stevens-Johnson syndrome

Mycoplasma pneumoniae

Full text is only available in PDF

Bibliografía

[1.]

J.C. Roujeau, R.S. Stern.

Severe adverse cutaneous reactions to drugs.

N Engl J Med, 331 (1994), pp. 1272-1285

http://dx.doi.org/10.1056/NEJM199411103311906 | Medline

[2.]

S.G. Baum.

Mycoplasma pneumoniae and atypical pneumonia.

Principles and practice of infectious diseases, 5th ed, pp. 2018-2027

[3.]

J.G. Barlett, R.F. Breiman, L.A. Mandell, T.M. File.

Community-acquired pneumonia in adults: guidelines for management.

Clin Infect Dis, 26 (1988), pp. 811-838

Medline

[4.]

T.J. Marrie, R.W. Peeling, M.J. Fine, D.E. Singer, C.M. Coley, W.N. Kapoor.

Ambulatory patients with community-acquired pneumonia: the frecuency of atypical agents and clinical course.

Am J Med, 101 (1996), pp. 508-515

Medline

[5.]

N.J. Ali, M. Sillis, B.E. Andrews, et al.

The clinical spectrum and diagnosis of Mycoplasma pneumoniae infection.

Qjm, 58 (1986), pp. 241

Medline

[6.]

D. Lieberman, F. Schaeleffer, I. Boldur, D. Lieberman, S. Horowitz, M.G. Friedman, et al.

Multiple pathogens in adult patients admitted with community-acquired pneumonia: a one year prospective study of 346 consecutive patients.

Thorax, 51 (1996), pp. 179-184

Medline

[7.]

Y.K. Tay, J.C. Huff, W.L. Weston.

Mycoplasma pneumoniae infection is associated with Stevens-Johnson syndrome, not erythema multiforme.

J Am Acad Dermatol, 35 (1996), pp. 757-760

Medline

[8.]

J.D. Cherry.

Anemia and mucocutaneous lesions due to Mycoplasma pneumoniae infections.

Clin Infect Dis, 17 (1993), pp. 47-51

[9.]

A. Auquier-Dunant, M. Mockenhaupt, L. Naldi, et al.

Correlation between clinical patterns and causes of erythema multiforme majus, Stevens-Johnson syndrome, and toxic epidermal necrolysis: results of an international prospective study.

Arch Dermatol, 138 (2002), pp. 1019-1024

Medline