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Vol. 56. Issue 1.
Pages 28-34 (January 2020)
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Vol. 56. Issue 1.
Pages 28-34 (January 2020)
Original Article
DOI: 10.1016/j.arbr.2019.04.019
Effects on Humidification and Ventilatory Parameters of Three Single-limb Heated-wired Circuits for Non-invasive Ventilation: A Bench Study
Efectos sobre la humidificación y los parámetros de ventilación de 3 circuitos de ramal único con cable calefactado para la ventilación mecánica no invasiva: estudio experimental
Jose M. Alonso-Iñigoa,
Corresponding author

Corresponding author.
, María J. Fasb, Alejandro Albertc, Abel Dolzd, Josèc) M. Carrataláe, Salvador Díaz-Lobatof
a Department of Anesthesiology, Critical Care and Pain Medicine, Hospital Universitari i Politècnic La Fe, Valencia, Spain
b Department of Hospital Managing, Hospital de Manises, Manises, Valencia, Spain
c Emergency Department, Hospital General Universitario de Alicante, Alicante, Spain
d Emergency Department, Hospital de Sagunto, Sagunto, Valencia, Spain
e Short-stay Medical Unit, Emergency Department, Hospital General Universitario de Alicante, Alicante, Spain
f Department of Pneumology, Hospital Universitario Ramón y Cajal, Madrid, Spain
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Figures (7)
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Tables (2)
Table 1. Absolute humidity (in mgH2O/L) of the medical gas with different heated wired-circuits at different FiO2 and IPAP levels. Data expressed as mean and standard deviation.
Table 2. Ventilator variables values with different heated wired-circuits at different IPAP levels. Data expressed as mean and standard deviation.
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The objective of this study was to evaluate the effects of three single-limb heated wired circuits (SLHWC) for NIV, on ventilatory parameters and humidification performance in a simulation lung model.


Three SLHWC compatible with the MR-850 Heated Humidifier (HH) (Fisher & Paykel, Auckland, New Zealand) were tested: RT-319 (FP) (Fisher & Paykel, Auckland, New Zealand), Respironics 1045770 (RP) (DEAS, Castel Bolognese, Italy) and Intersurgical B/SYS 5809001 (IT) (Intersurgical, Wokingham, UK). A Bipap Vision ventilator (Philips Respironics, Murrysville, PA, USA) in pressure control ventilation (PCV) connected to a test lung was used for simulation. Each SHWC performance was evaluated in four ventilatory conditions: IPAP of 15cmH2O with FiO2 0.3 and 1, respectively; and, IPAP of 25cmH2O with FiO2 0.3 and 1, respectively. EPAP was set at 5cmH2O. Hygrometric and ventilatory measurements including: relative humidity (RH), temperature (T), Pplat, PIP, PEEP, peak inspiratory flow (PIF), and tidal volume (Vt) were measured.


In each FiO2 group absolute humidity (AH) was similar with FP regardless of the IPAP level employed compared to IT and RP (P<.001). Except for RP at FiO2 0.3, AH increased significantly in IT and RP groups as IPAP increased (P<.001). PIP, Pplat, PEEP, PIF, and Vt values were significantly higher with FP and RP in each FiO2 group compared to IT (P<.001).


Humidification performance varied significantly among the three circuits, being FP the only one able to maintain stable AH values during the study with no influence on ventilatory parameters.

Heated humidifiers
Respiratory mechanics
Non-invasive ventilation
Mechanical ventilation

El objetivo de este estudio fue evaluar los efectos de 3 circuitos de ramal único (SLHWC) para la ventilación mecánica no invasiva (VNI) en los parámetros de ventilación y la humidificación en un modelo de simulación pulmonar.


Se evaluaron 3 SLHWC compatibles con el humidificador calefactado MR-850 (HH) (Fisher & Paykel, Auckland, Nueva Zelanda): RT-319 (FP) (Fisher & Paykel, Auckland, Nueva Zelanda), Respironics 1045770 (RP) (DEAS, Castel Bolognese, Italia) y Intersurgical B/SYS 5809001 (IT) (Intersurgical, Wokingham, Reino Unido). Para la simulación se empleó un ventilador Bipap Vision (Philips Respironics, Murrysville, PA, EE. UU.) con ventilación controlada por presión (PCV) conectado a un simulador pulmonar. El rendimiento de cada SHWC se evaluó en 4 condiciones ventilatorias: IPAP de 15cmH2O con FiO2 igual a 0,3 o igual a 1; IPAP de 25cmH2O con FiO2 igual a 0,3 o igual a 1. La EPAP se estableció en 5cmH2O. Las medidas ventilatorias e higromèc)tricas incluyeron: humedad relativa (HR) humedad absoluta (AH), temperature (T), Pplat, PIP, PEEP, pico de flujo inspiratorio (PIF) y volumen tidal (Vt).


Para cada grupo de FiO2 FP detectó valores similares de humedad absoluta (HA) en comparación con IT y RP (p<0,001), independientemente del nivel IPAP utilizado. Se registró un incremento significativo de la HA en todos los grupos medidos con IT y RP conforme aumentaron los valores de IPAP (p<0,001), excepto en el grupo de FiO2, igual a 0,3 medido con RP. Los valores de PIP, Pplat, PEEP, PIF y Vt resultaron significativamente más elevados con FP y RP en cada grupo FiO2 en comparación con IT (p<0,001).


La evaluación de la humidificación varió significativamente entre los 3 circuitos, siendo FP el único capaz de mantener estables los valores de HA durante el estudio sin influencia alguna de los parámetros ventilatorios.

Palabras clave:
Humidificadores calefactados
Mecánica respiratoria
Ventilación no invasiva
Ventilación mecánica


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