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Vol. 43. Issue 12.
Pages 662-668 (January 2007)
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Vol. 43. Issue 12.
Pages 662-668 (January 2007)
DOI: 10.1016/S1579-2129(07)60152-9
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Discriminative Properties and Validity of a Health Status Questionnaire in Obstructive Airway Disease Patients: The Airways Questionnaire 20
Aquiles Cameliera,
Corresponding author

Correspondence: Dr. A. Camelier. Respiratory Division, Universidade Federal da Bahia. Rua Manoel Andrade, 201; Ap. 401, Pituba Ville. Salvador, Ba. Brazil, ZIP 41810-815
, Fernanda W. Rosab, Oliver A. Nascimentoc, Ana Luiza G. Fernandesc, Jose R. Jardimc
a Respiratory Division, Faculdade de Tecnologia e Ciências (FTC), Universidade Federal da Bahia, Salvador, Bahia, Brazil
b Faculdade de Tecnologia e Ciências (FTC), Universidade Católica do Salvador, Universidade Estadual da Bahia (UNEB), Salvador, Bahia, Brazil
c Respiratory Division. Universidade Federal de São Paulo, São Paulo, Brazil
Article information

To evaluate the discriminative properties and validity of the Airways Questionnaire 20 (AQ20) in a sample of airway obstructed patients and to compare its properties with those of the St George's Respiratory Questionnaire (SGRQ) and the Short Form 36 (SF-36).


A convenience sample of 47 subjects was recruited from among 61 consecutive patients referred to an outpatient clinic specialized in airway obstructive diseases. All subjects completed the AQ20, SGRQ, and SF-36. Other measures were the baseline dyspnea index (BDI),6-minute walk test (6MWT) distance, spirometry, results of arterial blood gas analysis, and body mass index.


The AQ20 showed very good correlation with the SGRQ total score (ρ = 0.84, P < .001) and moderate correlation with all SF-36 domains (physical capacity, ρ = −0.53;physical functioning,ρ = −0.61;bodily pain, ρ = −0.55;general health,ρ = −0.59;vitality,ρ = − 0.55;;social functioning,ρ = −0.57; emotional role functioning,ρ = −0.51; mental health,ρ = −0.61;all P < .001).The BDI and the 6MWT were the best predictors of AQ20 score (r2 = 0.31) in the regression model. An area under the receiver operating characteristic curve of 0.91 (P < .001) indicated a high level of accuracy for the AQ20, using the SGRQ as the gold standard.


This study shows that the AQ20 is an accurate health status questionnaire in patients with moderate-to-severe airway obstruction. It could be an alternative to longer, traditional questionnaires such as the SGRQ.

Key words:
Quality of life
Health Status
Chronic obstructive pulmonary disease

Evaluar las propiedades discriminativas y la validez del cuestionario Airways Questionnaire 20 (AQ20) en un grupo de pacientes con cuadros de obstrucción de la vía respiratoria, y comparar sus propiedades con las de los cuestionarios St. George's Respiratory Questionnaire (SGRQ) y Short Form 36 (SF-36).


De un grupo de 61 pacientes consecutivos, remitidos a una consulta ambulatoria especializada en enfermedades obstructivas de la vía respiratoria, se seleccionó una muestra de conveniencia constituida por 47 pacientes. Todos los pacientes completaron los cuestionarios AQ20, SGRQ y SF-36.Otros parámetros evaluados fueron el índice de disnea basal, la distancia recorrida en la prueba de la marcha de 6 min, los resultados de la gasometría en sangre arterial y el índice de masa corporal.


El cuestionario AQ20 presentó una correlación estrecha con la puntuación del SGRQ total (ρ=0,84; p < 0,001) y una correlación moderada con todos los dominios del SF-36 (capacidad física,ρ=−0,53;actividad física, ρ=−0,61;dolor corporal,ρ=−0,55;salud general,ρ=−0,59; vitalidad,ρ=−0,55;actividad social,ρ=−0,57;actividad de rol emocional,ρ=−0,51;salud mental,ρ=−0,61;en todos los casos, p < 0,001).El índice de disnea basal y la distancia recorrida en la prueba de la marcha de 6 min fueron los mejores elementos predictivos de la puntuación del AQ20 (r2 = 0,31) en el modelo de regresión. El área bajo la curva de eficacia diagnóstica, que fue de 0,91 (p < 0,001), indicó un elevado grado de precisión del cuestionario AQ20, utilizando como prueba de referencia el SGRQ.


Los resultados obtenidos en este estudio demuestran que el AQ20 es un cuestionario preciso de salud en los pacientes con obstrucción de la vía respiratoria de grado moderado a intenso. Podría constituir una alternativa a los cuestionarios tradicionales más complejos, como el SGRQ.

Palabras clave:
Calidad de vida
Nivel de salud
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This study was partially supported by CAPES, CNPq, and FAPESP-Brazil.

Copyright © 2007. Sociedad Española de Neumología y Cirugía Torácica (SEPAR)
Archivos de Bronconeumología (English Edition)

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