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Vol. 43. Issue 12.
Pages 662-668 (January 2007)
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Vol. 43. Issue 12.
Pages 662-668 (January 2007)
ORIGINAL ARTICLES
DOI: 10.1016/S1579-2129(07)60152-9
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Discriminative Properties and Validity of a Health Status Questionnaire in Obstructive Airway Disease Patients: The Airways Questionnaire 20
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Aquiles Cameliera,
Corresponding author
aquilescamelier@yahoo.com.br

Correspondence: Dr. A. Camelier. Respiratory Division, Universidade Federal da Bahia. Rua Manoel Andrade, 201; Ap. 401, Pituba Ville. Salvador, Ba. Brazil, ZIP 41810-815
, Fernanda W. Rosab, Oliver A. Nascimentoc, Ana Luiza G. Fernandesc, Jose R. Jardimc
a Respiratory Division, Faculdade de Tecnologia e Ciências (FTC), Universidade Federal da Bahia, Salvador, Bahia, Brazil
b Faculdade de Tecnologia e Ciências (FTC), Universidade Católica do Salvador, Universidade Estadual da Bahia (UNEB), Salvador, Bahia, Brazil
c Respiratory Division. Universidade Federal de São Paulo, São Paulo, Brazil
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OBJECTIVE

To evaluate the discriminative properties and validity of the Airways Questionnaire 20 (AQ20) in a sample of airway obstructed patients and to compare its properties with those of the St George's Respiratory Questionnaire (SGRQ) and the Short Form 36 (SF-36).

PATIENTS AND METHODS

A convenience sample of 47 subjects was recruited from among 61 consecutive patients referred to an outpatient clinic specialized in airway obstructive diseases. All subjects completed the AQ20, SGRQ, and SF-36. Other measures were the baseline dyspnea index (BDI),6-minute walk test (6MWT) distance, spirometry, results of arterial blood gas analysis, and body mass index.

RESULTS

The AQ20 showed very good correlation with the SGRQ total score (ρ = 0.84, P < .001) and moderate correlation with all SF-36 domains (physical capacity, ρ = −0.53;physical functioning,ρ = −0.61;bodily pain, ρ = −0.55;general health,ρ = −0.59;vitality,ρ = − 0.55;;social functioning,ρ = −0.57; emotional role functioning,ρ = −0.51; mental health,ρ = −0.61;all P < .001).The BDI and the 6MWT were the best predictors of AQ20 score (r2 = 0.31) in the regression model. An area under the receiver operating characteristic curve of 0.91 (P < .001) indicated a high level of accuracy for the AQ20, using the SGRQ as the gold standard.

CONCLUSION

This study shows that the AQ20 is an accurate health status questionnaire in patients with moderate-to-severe airway obstruction. It could be an alternative to longer, traditional questionnaires such as the SGRQ.

Key words:
Questionnaires
Quality of life
Health Status
Statistics
Dyspnea
Chronic obstructive pulmonary disease
OBJETIVO

Evaluar las propiedades discriminativas y la validez del cuestionario Airways Questionnaire 20 (AQ20) en un grupo de pacientes con cuadros de obstrucción de la vía respiratoria, y comparar sus propiedades con las de los cuestionarios St. George's Respiratory Questionnaire (SGRQ) y Short Form 36 (SF-36).

PACIENTES Y MÉTODOS

De un grupo de 61 pacientes consecutivos, remitidos a una consulta ambulatoria especializada en enfermedades obstructivas de la vía respiratoria, se seleccionó una muestra de conveniencia constituida por 47 pacientes. Todos los pacientes completaron los cuestionarios AQ20, SGRQ y SF-36.Otros parámetros evaluados fueron el índice de disnea basal, la distancia recorrida en la prueba de la marcha de 6 min, los resultados de la gasometría en sangre arterial y el índice de masa corporal.

RESULTADOS

El cuestionario AQ20 presentó una correlación estrecha con la puntuación del SGRQ total (ρ=0,84; p < 0,001) y una correlación moderada con todos los dominios del SF-36 (capacidad física,ρ=−0,53;actividad física, ρ=−0,61;dolor corporal,ρ=−0,55;salud general,ρ=−0,59; vitalidad,ρ=−0,55;actividad social,ρ=−0,57;actividad de rol emocional,ρ=−0,51;salud mental,ρ=−0,61;en todos los casos, p < 0,001).El índice de disnea basal y la distancia recorrida en la prueba de la marcha de 6 min fueron los mejores elementos predictivos de la puntuación del AQ20 (r2 = 0,31) en el modelo de regresión. El área bajo la curva de eficacia diagnóstica, que fue de 0,91 (p < 0,001), indicó un elevado grado de precisión del cuestionario AQ20, utilizando como prueba de referencia el SGRQ.

CONCLUSIONES

Los resultados obtenidos en este estudio demuestran que el AQ20 es un cuestionario preciso de salud en los pacientes con obstrucción de la vía respiratoria de grado moderado a intenso. Podría constituir una alternativa a los cuestionarios tradicionales más complejos, como el SGRQ.

Palabras clave:
Cuestionarios
Calidad de vida
Nivel de salud
Estadística
Disnea
EPOC
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REFERENCES
[1]
PW Jones.
Health status measurement in chronic obstructive pulmonary disease.
Thorax, 56 (2001), pp. 880-887
[2]
FM Boueri, BL Bucher-Bartelson, KA Glenn, BJ Make.
Quality of life measured with a generic instrument (Short Form 36) improves following pulmonary rehabilitation in patients with COPD.
Chest, 119 (2001), pp. 77-84
[3]
A Camelier, FW Rosa, PW Jones, JR Jardim.
Brazilian version of airways questionnaire 20: a reproducibility study and correlations in patients with COPD.
Respir Med, 99 (2005), pp. 602-608
[4]
FH Quirk, PW Jones.
Back to basics: how many items can adequately represent health-related quality of life in airways disease?.
Eur Respir Rev, 7 (1997), pp. 50-52
[5]
FH Quirk, PW Jones.
Repeatability of two new short airways questionnaires.
Thorax, 49 (1994), pp. 1075-1079
[6]
T Hajiro, K Nishimura, PW Jones, M Tsukino, A Ikeda, H Koyama, et al.
A novel, short, and simple questionnaire to measure health- related quality of life in patients with chronic obstructive pulmonary disease.
Am J Respir Crit Care Med, 159 (1999), pp. 1874-1878
[7]
EA Barley, FH Quirk, PW Jones.
Asthma health status measurement in clinical practice: validity of a new short and simple instrument.
Respir Med, 92 (1998), pp. 1207-1214
[8]
T Oga, K Nishimura, M Tsukino, S Sato, T Hajiro, M Mishima.
Comparison of the responsiveness of different disease-specific health status measures in patients with asthma.
Chest, 122 (2002), pp. 1228-1233
[9]
B Alemayehu, RE Aubert, RA Feifer, LD Paul.
Comparative analysis of two quality-of-life instruments for patients with chronic obstructive pulmonary disease.
Value Health, 5 (2002), pp. 436-441
[10]
K Nishimura, T Hajiro, T Oga, M Tsukino, S Sato, A Ikeda.
A comparison of two simple measures to evaluate the health status of asthmatics: the Asthma Bother Profile and the Airways Questionnaire 20.
J Asthma, 41 (2004), pp. 141-146
[11]
LM Fabbri, SS Hurd.
Global Strategy for the Diagnosis, Management and Prevention of COPD: 2003 update.
Eur Respir J, 22 (2003), pp. 1-2
[12]
TE King Jr.
Bronchiolitis.
Interstitial lung diseases, 4th ed., pp. 654-684
[13]
Heart National.
Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland, USA. International consensus report on diagnosis and treatment of asthma.
Eur Respir J, 5 (1992), pp. 601-641
[14]
R Ciconelli, M Ferraz.
Translation to Portuguese and validation of the generic quality of life questionnaire: Medical Outcomes Study 36-Item Short Form Health Survey (SF-36).
Revista Brasileira de Reumatologia, 39 (1999), pp. 143-150
[15]
A Camelier, FW Rosa, C Salmi, OA Nascimento, F Cardoso, JR Jardim.
Using the Saint George's Respiratory Questionnaire to evaluate quality of life in patients with chronic obstructive pulmonary disease: validating a new version for use in Brazil.
J Bras Pneumol, 32 (2006), pp. 114-122
[16]
JE Ware, B Gandek.
International Quality of Life Assessment (IQLA) Project group: The SF-36 health survey.
Int J Ment Health, 23 (1994), pp. 49-73
[17]
M Ferrer, J Alonso, L Prieto, V Plaza, E Monso, R Marrades, et al.
Validity and reliability of the St George's Respiratory Questionnaire after adaptation to a different language and culture: the Spanish example.
Eur Respir J, 9 (1996), pp. 1160-1166
[18]
DA Mahler, DH Weinberg, CK Wells, AR Feinstein.
The measurement of dyspnea, contents, interobserver agreement, and physiologic correlates of two new clinical indexes.
Chest, 85 (1984), pp. 751-758
[19]
American Thoracic Society.
Single-breath carbon monoxide diffusing capacity (transfer factor). Recommendations for a standard technique–1995 update.
Am J Respir Crit Care Med, 152 (1995), pp. 2185-2198
[20]
ATS Statement: guidelines for the six minute walk test.
Am J Respir Crit Care Med, 166 (2002), pp. 111-117
[21]
LG Portney, MP Watkins.
Foundations of clinical research: applications to practice, pp. 529-553
[22]
R Antonelli-Incalzi, C Imperiale, V Bellia, F Catalano, N Scichilone, R Pistelli, et al.
Do GOLD stages of COPD severity really correspond to differences in health status?.
Eur Respir J, 22 (2003), pp. 444-449
[23]
JP de Torres, V Pinto-Plata, E Ingenito, P Bagley, A Gray, R Berger, et al.
Power of outcome measurements to detect clinically significant changes in pulmonary rehabilitation of patients with COPD.
Chest, 121 (2002), pp. 1092-1098
[24]
JA Chang, JR Curtis, DL Patrick, G Raghu.
Assessment of health- related quality of life in patients with interstitial lung disease.
Chest, 116 (1999), pp. 1175-1182

This study was partially supported by CAPES, CNPq, and FAPESP-Brazil.

Copyright © 2007. Sociedad Española de Neumología y Cirugía Torácica (SEPAR)
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