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Vol. 44. Issue 8.
Pages 424-427 (January 2008)
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Vol. 44. Issue 8.
Pages 424-427 (January 2008)
Original Articles
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Clinical and Functional Characteristics of Patients Prior to Lung Transplantation: Report of Experience at the Clínica Puerta de Hierro
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Rosalía Laporta
Corresponding author
roslaporta@terra.es

Correspondence: Dr R. Laporta Luna, 1 (2º, 2ª) 28220 Majadahonda, Madrid, Spain
, Piedad Ussetti, Gema Mora, Cristina López, David Gómez, Alicia de Pablo, M. Teresa Lázaro, M. Cruz Carreño, M. José Ferreiro
Servicio de Neumología, Clínica Puerta de Hierro, Madrid, Spain
Article information
Objective

The time at which lung transplantation is indicated is determined by clinical and functional criteria that vary according to the particular disease. The aim of our study was to present the criteria according to which patients were placed on waiting lists for lung transplantation in our hospital.

Patients and methods

We analyzed retrospectively the clinical characteristics, lung function, heart function, and 6-minute walk test results of patients who had received a lung transplant in our hospital from January 2002 through September 2005.

Results

During the study period 100 lung transplants were performed. The mean age of the patients was 45 years (range, 15–67 years) and 57% were men. The diseases that most often led to a lung transplant were chronic obstructive pulmonary disease (COPD) (35%), pulmonary fibrosis (29%), and bronchiectasis (21%). Lung function values differed by disease: mean (SD) forced expiratory volume in 1 second (FEV1) was 20% (11%) and forced vital capacity (FVC) was 37% (15%) in patients with COPD; FEV1 was 41% (15%) and FVC, 40% (17%) in patients with pulmonary fibrosis; and FEV1 was 23% (7%) and FVC, 37% (10%) in patients with bronchiectasis.

Conclusions

The patients who received lung transplants in our hospital were in advanced phases of their disease and met the inclusion criteria accepted by the various medical associations when they were placed on the waiting list.

Key words:
Lung transplantation
Lung disease
Spirometry
Selection of patients
Objetivo

El momento para indicar un trasplante pulmonar está definido por criterios clínicos y funcionales diferentes para cada enfermedad. El objetivo de este estudio es presentar cuáles fueron los criterios por los que en nuestro hospital se incluyó a los pacientes en lista de espera de trasplante pulmonar.

Pacientes y métodos

Se ha realizado un análisis retrospectivo de las características clínicas, la función respiratoria, la prueba de la marcha de 6 minutos y el estudio cardiológico de los pacientes que recibieron un trasplante pulmonar entre enero de 2002 y septiembre de 2005.

Resultados

En el período estudiado se realizaron 100 trasplantes pulmonares. La edad media de los pacientes era de 45 años (rango: 15–67) y el 57% eran varones. Las enfermedades que con mayor frecuencia motivaron el trasplante pulmonar fueron la enfermedad pulmonar obstructiva crónica (EPOC, 35%), la fibrosis pulmonar (29%) y las bronquiectasias (BQ) (21%). La media ± desviación estándar de la función pulmonar osciló entre el 20 ± 11% del volumen espiratorio forzado en el primer segundo (FEV1) y el 37 ± 15% de la capacidad vital forzada (FVC) en la EPOC; del 41 ± 15% del FEV1 y el 40 ± 17% de la FVC en la fibrosis pulmonar, y del 23 ± 7% del FEV1 y el 37 ± 10% de la FVC en las BQ.

Conclusiones

Los pacientes que recibieron un trasplante pulmonar en nuestro centro se encontraban en fases muy evolucionadas de su enfermedad y cumplían los criterios de inclusión admitidos por las diferentes sociedades médicas cuando se les incluyó en lista de espera.

Palabras clave:
Trasplante pulmonar
Enfermedad pulmonar
Espirometría
Selección de pacientes
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Copyright © 2008. Sociedad Española de Neumología y Cirugía Torácica (SEPAR)
Archivos de Bronconeumología

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