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Vol. 25. Issue 5.
Pages 184-186 (June - July 1989)
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Vol. 25. Issue 5.
Pages 184-186 (June - July 1989)
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Timomas: estudio clinico-patologico y factores pronosticos en 20 pacientes
Thymoma: a clinico-pathological study and prognostic factors in 20 patients
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J. Lluís, L. Molins, M. Galofré
Servicios de Cirugía General. Hospital de la Creu Roja. Universitat Autònoma. Barcelona
F. Rodríguez-Méndez*
* Servicios de Anatomía Patológica. Hospital de la Creu Roja. Universitat Autònoma. Barcelona
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Se analizan retrospectivamente las características clínicas, tipo histológico, factores pronósticos y resultados de la cirugía correspondientes a 20 pacientes con timoma. Doce presentaban miastenia gravis y dos polimiositis asociadas. El timoma era encapsulado en 12 casos e invasivo en 8. El tipo histológico más frecuente fue el linfoepitelial (11 casos). Los doce timomas encapsulados pudieron ser resecados, pero dos pacientes con miastenia fallecieron en el postoperatorio inmediato. Los restantes 10 están sanos entre 3 meses y 14 años tras la cirugía (media 8,7 años). En el grupo de 8 timomas invasivos, 5 fueron biopsiados y 3 resecados. Los pacientes con tumor irresecable recibieron radioterapia postoperatoria. Tres pacientes fallecieron de su timoma entre los 6 meses y 5 años postoperatorios, dos de ellos con metástasis intraabdominales. Los tres pacientes con timoma invasivo resecado continúan viviendo al año, 3 y 19 años tras la cirugía, pero uno de ellos con resección paliativa ha precisado dos nuevas reintervenciones por recidivas locales y radioterapia adicional.

The clinical features, histological type, prognostic factors, and resids ofsurgical treatment were retrospectively evaluated in 20 patients with thymoma. Twelve had myasthenia gravis and two had associated polymyosytis. Thymoma was encapsulated in 12 cases and invasive in 8. The most common histological type was lymphoepithelial (11 cases). The 12 encapsulated thymomas could be resected, but two patients with myasthenia died in the immediate postoperative period. The remaining 10 patients are healthy 3 months-14 years after surgery (mean 8,7 years). In the group of 8 invasive thymomas, biopsy was carried out in 8 and resection in 3. The patients in whom the tumor could not be resected underwent postoperative radiotherapy. Three patients died of thymoma between 6 months and 5 years after surgery, two of them with intraabdominal metastases. The three patients in whom invasive thymoma was resected are still alive 1, 3 and 19 years after surgery. However, one of them, in whom resection was palliative, required two new operations due to local relapse and additional radiotherapy.

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Copyright © 1989. Sociedad Española de Neumología y Cirugía Torácica
Archivos de Bronconeumología
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