Original articlePrevalence and predictive factors of sleep apnoea syndrome in type 2 diabetic patientsPrévalence et facteurs prédictifs de syndrome d’apnées du sommeil chez des patients présentant un diabète de type 2
Section snippets
Study population
Participation in the present study was proposed to all patients admitted over a 6-month period—from January to June 2007—to the Department of Diabetology at our hospital with poorly controlled type 2 diabetes, as assessed by one hospital staff doctor during an outpatients visit. The diabetic patients found to be poorly controlled (based on clinical and biological data) were hospitalized for an average of 1 to 5 days for various clinical examinations and patient education.
Every hospitalized
Results
A total of 362 patients with type 2 diabetes were hospitalized during the study period because of poor diabetic control, of which 23 (6%) had already been diagnosed with sleep apnoea. Thirty-two patients fulfilled the exclusion criteria and were excluded. Also, in four cases, it was impossible to analyze the polygraphy due to technical failure. The remaining 303 patients (156 men, 147 women) were finally included in the study.
The prevalence of newly diagnosed SAS was 63% (191/303) in these
Discussion
In the present study, we systematically performed nocturnal respiratory polygraphic studies in 303 patients consecutively admitted to hospital because of poorly controlled type 2 diabetes. We found that the prevalence of previously undiagnosed SAS was high in these patients, reaching 63%. Also, nearly all of the apnoeic patients had the obstructive form of the condition, whereas the prevalence of obstructive SAS in the general population is much lower, ranging from 2 to 9% [16]. In addition,
Conflicts of interests
The authors do not have any conflict of interests to declare regarding the present study.
References (35)
- et al.
The prevalence and cost of diabetes in metropolitan France: what trends between 1998 and 2000?
Diabetes Metab
(2003) - et al.
Screening for diabetes in France: data from the 2000–2001 cohort of the National Medical Insurance System
Rev Epidemiol Sante Publique
(2004) - et al.
Obstructive sleep apnea and type 2 diabetes: interacting epidemics
Chest
(2008) - et al.
Obstructive sleep apnea and cardiovascular disease
J Am Coll Cardiol
(2003) - et al.
Obstructive sleep apnea and cardiovascular disease
Mayo Clin Proc
(2004) Sleep-disordered breathing and cardiovascular disease
Sleep Med Rev
(2005)- et al.
Long-term cardiovascular outcomes in men with obstructive sleep apnoea-hypopnoea with or without treatment with continuous positive airway pressure: an observational study
Lancet
(2005) - et al.
Metabolic syndrome and risk of cardiovascular disease: a meta-analysis
Am J Med
(2006) - et al.
The evolving diabetes burden in the United States
Ann Intern Med
(2004) - et al.
Impaired glucose-insulin metabolism in males with Obstructive sleep apnoea syndrome
Eur Respir J
(2003)
Association of sleep apnea and type II diabetes. A population-based study
Am J Respir Crit Care Med
Prevalence of obstructive sleep apnoea in men with type 2 diabetes
Thorax
Diabetes and sleep disturbances: findings from the Sleep Heart Health Study
Diabetes Care
Obstructive sleep apnea is independently associated with insulin resistance
Am J Respir Crit Care Med
Sleep-disordered breathing and insulin resistance in middle-aged and overweight men
Am J Respir Crit Care Med
Sleep-disordered breathing, glucose intolerance, and insulin resistance: the Sleep Heart Health Study
Am J Epidemiol
Type 2 diabetes, glycemic control, and continuous positive airway pressure in obstructive sleep apnea
Arch Intern Med
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2020, Diabetes Research and Clinical PracticeCitation Excerpt :We included studies that measured sleep disorders using hospital tele-monitored polysomnography, home unattended polysomnography, chart review, or physician’s diagnosis. Of the 41 studies included, the majority had relatively good quality: 24 studies were classified as good quality studies [11,16-18,20,23–25,29,34–38,42,44–50,53], 13 studies were categorized as fair quality studies [10,19,21,22,26,27,29–33,39,43] and 5 studies were classified as poor due to potential selection bias or poor exposure definition [11,28,41,51,52]. After excluding the poor-quality studies (n = 5), thirty-six studies were included in the meta-analysis.