Radiology resident educationInteractive High-resolution Computed Tomography Digital Atlas of Interstitial Lung Disease
Section snippets
Image Acquisition and Disease Selection
All HRCT examinations were performed from 2000 through 2010 on a 16-slice or 64-slice scanner. Most studies were performed using a standard HRCT protocol. Axial sections were acquired at 0.625-mm collimation in deep suspended inspiration and reconstructed at 1.5 mm. Images were displayed at a window width of 1000 to 1600 and a mean of −600 to −700. The field of view was approximately 35 cm. Images for the digital atlas were taken at 16 proximate predetermined levels from the inspiratory
UIP
Patients with UIP are usually >50 years of age, with a clinical presentation of slowly progressive dyspnea, nonproductive cough, and weight loss 5, 6, 7. Most patients have a median survival of 2.5 to 3.5 years from symptom onset (8). Lung transplantation may be curative. Histologic analysis reveals normal lung next to fibrotic lung. Within the fibrotic lung is evidence of early and active fibrosis defined by fibroblastic foci as well as dense mature fibrosis indicating a chronic process. The
Conclusions
We have provided a free interactive HRCT digital atlas of varying presentations of ILD and a brief review of ILD. With this software, users are able to test their knowledge of the idiopathic ILDs through the use of unknowns and unlabeled images as described in the appendices. A detailed discussion of the imaging findings and appropriate differential diagnosis accompanies each case. The spectrum of disease is substantial in the same ILD and among the different ILDs. In a future study, we plan to
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Cited by (2)
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2013, Respiratory InvestigationCitation Excerpt :The study protocol was approved by the Research Ethics Committee of Japan Railway Tokyo General Hospital, and all patients provided informed consent prior to initiation of the study. To validate the presence of characteristic HRCT findings of subjects, namely centrilobular nodular (CN) shadows, GGOs, emphysematous changes, and interstitial changes [13,14], all images were analyzed by 2 pulmonologists independently (Y.Y and C.K). The lung carcinoma lesion and a region macroscopically distant from the lung carcinoma were histopathologically examined in each patient.