Original contributionDown syndrome: Patterns of disturbed lung growth☆
References (18)
- et al.
Pulmonary hypoplasia in Down's syndrome
N Engl J Med
(1982) - et al.
Diminished radial count found only postnatally in Down's syndrome
Pediatr Pulmonol
(1988) - et al.
Intrasegmental airway generations and radial alveolar counts in Down's syndrome—Patterns of disturbed lung growth
Am Rev Respir Dis suppl
(1987) Postnatal human lung growth
Thorax
(1982)- et al.
Development of the intrasegmental bronchial tree: The pattern of branching and development of cartilage at various stages of intrauterine life
Thorax
(1961) - et al.
Observations on the anatomy of the intrasegmental bronchial tree
Thorax
(1952) - et al.
The number of alveoli in the terminal respiratory unit of man during late intrauterine life and childhood
Arch Dis Child
(1960) - et al.
The radial alveolar count of Emery and Mithal: A reappraisal. 1—Postnatal lung growth
Thorax
(1982) - et al.
The radial alveolar count method of Emery and Mithal: A reappraisal. 2—Intrauterine and early postnatal lungs
Thorax
(1982)
Cited by (57)
Recent Advances in Pediatric Pulmonary Hypertension: Implications for Diagnosis and Treatment
2023, Clinical TherapeuticsPulmonary Hypertension in Children with Down Syndrome: Results from the Pediatric Pulmonary Hypertension Network Registry
2023, Journal of PediatricsCitation Excerpt :We acknowledge that we may have overestimated the percentage of persistent CHD cases in the registry, given that data pertaining to repair status were limited to the time of enrollment and spontaneous closure of defects was not specifically queried. Growing evidence suggests that children with Down syndrome have insufficient lung development consistent with a lung hypoplasia phenotype.13,14 Bush et al demonstrated that the underdeveloped pulmonary vascular and alveolar phenotype in patients with Down syndrome is similar to that in the lungs of infants with prematurity-associated bronchopulmonary dysplasia, which likely contributes to the increased incidence and severity of pulmonary hypertension.12
Developmental and pediatric lung disease
2022, Practical Pulmonary Pathology: A Diagnostic ApproachPulmonary Cystic Disease and Its Mimics
2020, Surgical Pathology ClinicsCitation Excerpt :There is a strong association of pleuropulmonary blastoma with DICER1 mutations.18 Occasionally, cases of numerous peripheral cysts, similar to paraseptal emphysema, but often with mild associated fibrosis, have been described in patients with trisomy 21.19 These cysts tend to be subpleural, but can be found in both the apex and the base.
Quality of Pulmonary Function Tests in Participants with Down Syndrome
2019, Archivos de BronconeumologiaCitation Excerpt :Down syndrome (DS) is a genetic alteration characterized by trisomy of chromosome 21.1 People with DS have high respiratory morbidity associated with structural, functional and immunological alterations that have substantial impacts in the medium term.2–4 Thus, evaluating the respiratory health of people with chronic respiratory symptoms using standardized, objective tests is desirable.
Intrathoracic Cystic Lesions in Neonates and Children
2018, Practical Pulmonary Pathology: A Diagnostic Approach A Volume in the Pattern Recognition Series
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Supported by grant no. HLBI SCOR 32363.