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Available online 4 March 2026

Pseudomembranous Tracheobronquitis Presenting as a Late Complication of Unilateral Lung Transplantation

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Natalia de Cabo Bovéa, Ana Lucía Sáncheza,b, Ivan Vollmera,c,
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ivan.vollmer@vallhebron.cat

Corresponding author.
a Servei de Radiologia, Vall d’Hebron Hospital Universitari, Vall d’Hebron Barcelona Hospital Campus, Passeig Vall d’Hebron 119-129, 08035 Barcelona, Spain
b IDI (Institut de Diagnòstic per la Imatge) – Vall d’Hebron, Spain
c Biologia Vascular i Metabolisme (VAM), Imatge Mèdica Molecular, Serveis Diagnòstic per la Imatge (Radiologia), Vall d’Hebron Institut de Recerca (VHIR), Vall d’Hebron Hospital Universitari, Vall d’Hebron Barcelona Hospital Campus, Passeig Vall d’Hebron 119-129, 08035 Barcelona, Spain
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We present the case of a 72-year-old patient with a history of right lung transplantation (February 2018) treated with tacrolimus and rapamycin, who in October 2024 presented deterioration of lung function. A thoracic CT scan was performed in which tracheobronchial involvement was observed, with irregularity of the posterior wall of the trachea and bronchi, and formation of saccular dilations and tracheal pseudomembranes (Fig. 1). All this suggested a pseudomembranous tracheobronchitis secondary to subacute fungal infection. A bronchoscopy confirmed the presence of Aspergillus terreus, and treatment with isavuconazole and inhaled voriconazole was administered. Pseudomembranous tracheobronchitis is a condition in which pseudomembranes form in the trachea and bronchi, obstructing the airways and making it difficult to breathe. Its etiology can be bacterial, fungal, or related to connective tissue diseases. Chest CT scans show thickening of the tracheal and bronchial walls (Fig. 1), pseudomembranes (Fig. 1), airway obstruction, and pulmonary involvement such as atelectasis or consolidation [1]. Treatment is based on identifying the cause and giving appropriate treatment [2–4].

Fig. 1.

(A, B) CT scan showing formation of saccular dilations and tracheal pseudomembranes on the trachea and main bronchi (black and white arrows). (C) CT scan in a sagittal view showing affectation of the anterior and posterior walls of the trachea (white arrows). (D) MPR reconstruction of the trachea and right main bronchus showing an extensive mural disease (white ellipse).

Artificial intelligence involvement

The authors declare that they have not used Artificial Intelligence tools in the writing of this paper.

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None declared.

Conflicts of interest

The authors declare that they have no conflicts of interest.

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