TY - JOUR T1 - Incidence and Prevalence of Children's Diffuse Lung Disease in Spain JO - Archivos de Bronconeumología T2 - AU - Torrent-Vernetta,Alba AU - Gaboli,Mirella AU - Castillo-Corullón,Silvia AU - Mondéjar-López,Pedro AU - Sanz Santiago,Verónica AU - Costa-Colomer,Jordi AU - Osona,Borja AU - Torres-Borrego,Javier AU - de la Serna-Blázquez,Olga AU - Bellón Alonso,Sara AU - Caro Aguilera,Pilar AU - Gimeno-Díaz de Atauri,Álvaro AU - Valenzuela Soria,Alfredo AU - Ayats,Roser AU - Martin de Vicente,Carlos AU - Velasco González,Valle AU - Moure González,José Domingo AU - Canino Calderín,Elisa María AU - Pastor-Vivero,María Dolores AU - Villar Álvarez,María Ángeles AU - Rovira-Amigo,Sandra AU - Iglesias Serrano,Ignacio AU - Díez Izquierdo,Ana AU - de Mir Messa,Inés AU - Gartner,Silvia AU - Navarro,Alexandra AU - Baz-Redón,Noelia AU - Carmona,Rosario AU - Camats-Tarruella,Núria AU - Fernández-Cancio,Mónica AU - Rapp,Christina AU - Dopazo,Joaquin AU - Griese,Matthias AU - Moreno-Galdó,Antonio SN - 03002896 M3 - 10.1016/j.arbres.2021.06.001 DO - 10.1016/j.arbres.2021.06.001 UR - https://www.archbronconeumol.org/en-incidence-prevalence-children39s-diffuse-lung-articulo-S0300289621001812 AB - BackgroundChildren's diffuse lung disease, also known as children's Interstitial Lung Diseases (chILD), are a heterogeneous group of rare diseases with relevant morbidity and mortality, which diagnosis and classification are very complex. Epidemiological data are scarce. The aim of this study was to analyse incidence and prevalence of chILD in Spain. MethodsMulticentre observational prospective study in patients from 0 to 18 years of age with chILD to analyse its incidence and prevalence in Spain, based on data reported in 2018 and 2019. ResultsA total of 381 cases with chILD were notified from 51 paediatric pulmonology units all over Spain, covering the 91.7% of the paediatric population. The average incidence of chILD was 8.18 (CI 95% 6.28–10.48) new cases/million of children per year. The average prevalence of chILD was 46.53 (CI 95% 41.81–51.62) cases/million of children. The age group with the highest prevalence were children under 1 year of age. Different types of disorders were seen in children 2–18 years of age compared with children 0–2 years of age. Most frequent cases were: primary pulmonary interstitial glycogenosis in neonates (17/65), neuroendocrine cell hyperplasia of infancy in infants from 1 to 12 months (44/144), idiopathic pulmonary haemosiderosis in children from 1 to 5 years old (13/74), hypersensitivity pneumonitis in children from 5 to 10 years old (9/51), and scleroderma in older than 10 years old (8/47). ConclusionsWe found a higher incidence and prevalence of chILD than previously described probably due to greater understanding and increased clinician awareness of these rare diseases. ER -