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Vol. 24. Issue 3.
Pages 110-113 (May - June 1988)
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Vol. 24. Issue 3.
Pages 110-113 (May - June 1988)
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El lavado broncoalveolar en pacientes con diagnostico o alta sospecha de SIDA
Bronchoalveolar lavage in patients diagnosed or higly suspicious of AIDS
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J.L. Izquierdo Alonso, J.M. Rodriguez Glez.-Moro, L. Puente Maeztu, P. Lucas Ramos, E. Tatay Martin, J.M. Monturiol Rodriguez
Servicio de Neumología. Hospital General Gregorio Marañón. Madrid
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Se estudia con carácter prospectivo la rentabilidad del lavado broncoalveolar (LBA) como método diagnóstico en las complicaciones infecdosas pulmonares de un grupo de 33 parientes con diagnóstico (22) o alta sospecha de SIDA (11) y afectación pulmonar. El LBA fue positivo en 15 exploradones. El seguimiento posterior incluyendo necropsia, biopsia pulmonar o evolución clínica mostró una rentabilidad del 80% para P. carinii y del 81,8% para M. tuberculosis que fueron los patógenos más frecuentes. No se demostró ningún caso de afectarión por citomegalovirus (CMV), micobacterias atípicas ni hongos, detectándose por necropsia un falso negativo de afectación por CMY. No se produjeron complicaciones relevantes en ninguna de las exploradones. Los resultados confirman que el LBA es un método seguro y eficaz, constituyendo, en nuestra opinión, el primer método diagnóstico de elecdón en las complicaciones infecciosas pulmonares del SIDA.

A prospespective study is made of the profitability of bronchoalveolar lavage (LBA) as a diagnostic method of lung infections complications in a group of 33 patients diagnosed22 or highly suspicious of AIDS11 and pulmonary affection. The bronchoalveolar lavage was positive in 15 examinations. Further follow-up induding necropsy, lung biopsy or clinical evolution showed a profitability of 80% for P. carinii and of 81,8% for M. tuberculosis that were the most common pathogens. No cases of cytomegalovirus (CMV), atypical mycobacteria or fungi were demonstrated, and false negative of cytomegalovirus affection was detected by necropsy. No outstanding complications happened in any of the examinatíons. The outcomes confirm that the bronchoalveolar lavage is a reliable and effectíve method, that constitutes, in our opinion, the first diagnostic method of choice in the lung infectious complications of AIDS.

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Bibliografía
[1.]
P.C. Hopewell, J.M. Luce.
Pulmonary involvement in the acquired inmunodeficiency syndrome.
Chest, 87 (1985), pp. 104-112
[2.]
J. Kelley, J.N. Landis, G.S. Davis, T.D. Trainer, G.J. Jakab, G.M. Green.
Diagnosis of pneumonia due to pneumocystis by subsegmental pulmonary lavage via the fibreoptic bronchoscope.
Chest, 74 (1978), pp. 24-28
[3.]
P.C. Goodman, C.V. Broaddus, P.C. Hopewell.
Chest radiographic patterns in the acquired immunodeficiency syndrome.
Am Rev Respir Dis, 129 (1984), pp. A.36
[4.]
U. DeLorenzo, C.T. Huang, G.P. Maguire, D.J. Stone.
Roentgenographic patterns of Pneumocystis carinii pneumonia in 104 patients with the acquired immunodeficiency syndrome.
Am Rev Resp Dis, 133 (1986), pp. A.81
[5.]
F.M. Gordin, G.L. Simon, C.B. Wofsy, J. Mills.
Adverse reactions to trimethoprimsulfamethoxazole with the acquired immunodeficiency syndrome.
Ann Intern Med, 100 (1984), pp. 495-499
[6.]
A.E. Pitchenik, P. Ganjei, A. Torres, D.A. Evans, E. Rubin, H. Baier.
Sputum examination for the diagnosis of Pneumocystis carinii pneumonia in the acquired immunodeficiency syndrome.
Am Rev Respir Dis, 133 (1986), pp. 226-229
[7.]
S.M. Brown, L. Sithole, C. Aranda.
Induced sputum in the diagnosis of Pneumocystis carinii pneumonia.
Am Rev Respir Dis, 133 (1986), pp. A180
[8.]
T.D. Bigby, D. Margolskee, J.L. Curtis, et al.
The usefulness of induced sputum in the diagnosis of Pneumocystis carinii pneumonia in patients with the acquired immunodeficiency syndrome.
Am Rev Respir Dis, 133 (1986), pp. 515-518
[9.]
R.J. McKenna, A. Campbell, M.J. McMurtrey, C.F. Mountain.
Diagnosis for interstitial lung disease in patients with acquired immunodeficiency syndrome (AIDS). A prospective comparison of bronchial washing, alveolar lavage, transbronchial lung biopsy and open-lung biopsy.
Ann Thorac Surg, 41 (1986), pp. 318-321
[10.]
H.I. Pass, D. Potter, J. Shehammer, et al.
Indications for and diagnostic efficacy of open lung biopsy in the patient with acquired immunodeficiency syndrome (AIDS).
Ann Thorac Surg, 41 (1986), pp. 307-312
[11.]
D.L. Coleman, P.M. Dodek, J.M. Luce, J.A. Golden, W.M. Gold, J.F. Murray.
Diagnostic utility of fiberoptic bronchoscopy in patients with Pneumocystis carinii pneumonia and the acquired immune deficiency syndrome.
Am Rev Respir Dis, 128 (1983), pp. 795-799
[12.]
W. Blumenfeld, E. Wagar, W.K. Hadly.
Use of the transbronchial biopsy for diagnosis of opportunistic pulmonary infections in acquired immunodeficiency syndrome (AIDS).
Am J Clin Pathol, 81 (1984), pp. 1-5
[13.]
G. Caughey, H. Wong, G. Gamsu, J. Golden.
Nonbronchoscopic bronchoalveolar lavage for the diagnosis for Pneumocystis carinii pneumonia in the acquired immunodeficiency syndrome.
Chest, 88 (1985), pp. 659-662
[14.]
M.J. Rosen, T.W. Tow, A.S. Terstein, M.T. Chuang, A. Marchevsky, E.J. Bottone.
Diagnosis of pulmonary complications of the acquired immunodeficiency syndrome.
Thorax, 40 (1985), pp. 571-575
[15.]
D.E. Stover, D.A. White, P.A. Romano, R.A. Gallene.
Diagnosis of pulmonary disease in acquired immunodeficiency syndrome.
Am Rev Respir Dis, 130 (1984), pp. 659-662
[16.]
M. Orenstein, C.A. Webber, M. Cash, A.E. Heurich.
Value of bronchoalveolar lavage in the diagnosis of pulmonary infection in acquired immunodeficiency syndrome.
Thorax, 41 (1986), pp. 345-349
[17.]
J.F. Murray, C.P. Felton, S.M. Garay, et al.
Pulmonary complications of the acquired immunodeficiency syndrome; report of a National Heart. Lung and Blood Institute Workshop.
N Engl J Med, 310 (1984), pp. 1682-1688
[18.]
F.P. Ognibene, J. Shelhamer, V. Gill, et al.
The diagnosis of Pneumocystis carinii pneumonia in patients with the acquired immunodeficiency syndrome using subsegmental bronchoalveolar lavage.
Am Rev Respir Dis, 129 (1984), pp. 929-932
[19.]
J.M. Mones, M.J. Saldana, S.A. Oldham.
Diagnosis of Pneumocystis carinii pneumonia. Roentgenographic-pathologic correlates based on fiberoptic bronchoscopy specimens from patients with the acquired immunodeficiency syndrome.
Chest, 89 (1986), pp. 522-526
[20.]
C. Broaddus, M.D. Dake, M.S. Stulbarg, et al.
Bronchoalveolar lavage and transbronchial biopsy for the diagnosis of pulmonary infections in the acquired immunodeficiency syndrome.
Ann Int Med, 102 (1985), pp. 747-752
[21.]
J.A. Golden, H. Hollander, M.S. Stulbarg, G. Gamsu.
Bronchoalveolar lavage as the exclusive diagnostic modality for Pneumocystis carinii pneumonia. A prospective study among patients with acquired immunodeficiency syndrome.
Chest, 90 (1986), pp. 18-22
[22.]
D.E. Stover, D.A. White, P.A. Romano, R.A. Gellene, W.A. Robeson.
Spectrum of pulmonary diseases associated with the acquired immunodeficiency syndrome.
Am J Med, 78 (1985), pp. 429-437
[23.]
J.F. Murray, S.M. Garay, P.C. Hopewell, J. Mills, G.L. Snider, D.E. Stover.
Pulmonary complications of the acquired immunodeficiency syndrome: An update; report of second National Heart. Lung and Blood Institute Workshop.
Am Rev Respir Dis, 135 (1987), pp. 504-509
[24.]
H.C. Lane, H. Masur, L.C. Edgar, G. Whalen, A.H. Rook, A.S. Fauci.
Abnormalities of B-cell activation and immunoregulation in patients with the acquired immunodeficiency syndrome.
N Eng J Med, 309 (1983), pp. 453-458
[25.]
S.M. Winter, E.M. Bernard, J.W.M. Gold, D. Amstrong.
Humoral response to disseminated infection by Mycobacterium avium-mycobacterium intracellulare in acquired immunodeficiency syndrome and hairy cell leukemia.
J Infect Dis, 151 (1985), pp. 523-527
[26.]
A.J. Ammann, G. Schiffman, D. Abrams, P. Volberding, J. Ziegler, M. Conant.
B. Cell immunodeficiency in acquired immunodeficiency syndrome.
JAMA, 251 (1984), pp. 1447-1449
[27.]
A.S. Fauci, A.M. Macher, D.L. Longo, et al.
Acquired immunodeficiency syndrome: epidemiologic, clinical, immunologic and therapeutic considerations.
Ann Intern Med, 100 (1984), pp. 92-106
[28.]
A.J. Amman, D. Abrams, M. Conant, et al.
Acquired immune dysfunction in homosexual men: immunologic profiles.
Clin Immunol Immunopathol, 27 (1983), pp. 315-325
[29.]
B. Polsky, J.W.M. Gold, E. Whimbey, et al.
Bacterial pneumonia in patients with the acquired immunodeficiency syndrome.
Ann Int Med, 104 (1986), pp. 38-41
[30.]
N. Wimberley, L.J. Faling, J.G. Bartlett.
A fiberoptic bronchoscopy technique to obtain uncontamined lower airway secretions for bacterial culture.
Am Rev Respir Dis, 119 (1979), pp. 337-343
[31.]
N.W. Wimberley, J.B. Bass, B.W. Boyd, M.B. Kirkpatrick, R.A. Serio, H.M. Pollock.
Use of a bronchoscopic protected catheter brush for the diagnosis of pulmonary infections.
Chest, 81 (1982), pp. 556-562
[32.]
E.C. Fletcher, J.A. Mohr, D.C. Levin, D.J. Flournoy, T. Jhonson.
Bacteriologic diagnosis of pneumonia with protected specimen brush and fiberoptic bronchoscopy.
Am Rev Respir Dis, 121 (1980), pp. A.134
[33.]
P. Legrand, J.Y. Bordelon, W.C. Gewin, et al.
The telescoping plugged catheter in suspected anaerobic infections: A controlled serie.
Am Rev Respir Dis, 121 (1980), pp. A.157
[34.]
D.A. Hayes, L.C. McCarthy, M. Friedman.
Evaluation of two bronchofiberscopic methods of culturing the lower respiratory tract flora.
Am Rev Respir Dis, 122 (1980), pp. 319-323
[35.]
V. Ausina, M.J. Condom.
Tuberculosis y virus de la immunodeficiencia humana.
Arch Bronconeumol, 23 (1987), pp. 161-163
[36.]
Center for Disease Control.
Tuberculosis-United States, 1985 and the possible impact of human T-lymphotropic virus tipe III/lymphadenopathy-associated virus infection.
MMWR, 35 (1986), pp. 7476
[37.]
Case Record of the Massachusetts General Hospital.
Case 2-1986.
N Engl J Med, 314 (1986), pp. 167-174
[38.]
E. Louie, L.B. Rice, R.S. Holzman.
Tuberculosis in non-haitian patients with acquired immunodeficiency syndrome.
Chest, 90 (1986), pp. 542-545
[39.]
C.C. Hawkins, J.W.M. Gold, E. Whimbey, et al.
Mycobacterium avium complex infections in patients with the acquired imunodeficiency syndrome.
Ann Inter Med, 105 (1986), pp. 184-188
[40.]
O.G. Berlin, P. Zakowski, D.A. Bruckner, M.N. Clancy, B.L. Jhonson.
Mycobacterium avium: a pathogen of patients with acquired immunodeficiency syndrome.
Diagn Microbiol Infect Dis, 2 (1984), pp. 213-218
[41.]
J.B. Greene, G.S. Sidhu, S. Lewin, et al.
Mycobacterium aviumintracellulare: a cause of disseminated life threatening infection in homosexuals and drugs abusers.
Ann Intern Med, 97 (1982), pp. 539541
[42.]
Center for Disease Control.
Diagnosis and management of mycobacterial infection and disease in persons with human-TLymphotropic virus type III/lymphadenopathy-associated virus infection.
MMWR, 36 (1986), pp. 448-452
[43.]
J. Cosin, C. Martín-Scapa, J. Menarguez, E. Bouza.
SIDA y tuberculosis.
Enf Infecc y Microbiol Clin, 5 (1987), pp. 74-80
[44.]
A. De la Loma, A. Manrique, R. Rubio, et al.
Generalised tuberculosis in a patient with acquired immunodeficiency syndrome.
J Infect, 10 (1985), pp. 57-59
[45.]
J.M. Aguado García, J.M. Castrillo García.
Síndrome de imunodeficiencia adquirida para países pobres; ¿tuberculosis diseminada como infección oportunista en drogadictos?.
Med Clin (Barc), 86 (1986), pp. 132-133
[46.]
A.E. Pitchenik, C. Cole, B.W. Russell, M.A. Fischl, T.J. Spira, D.E. Snider.
Tuberculosis, atypical mycobacteriosis and the acquired immunodeficiency syndrome among haitian and non haitian patients in South Florida.
Ann Intern Med, 101 (1984), pp. 641-645
[47.]
Center for Disease Control.
Tuberculosis and acquired immunodeficiency syndrome-Florida.
MMWR, 35 (1986), pp. 587-590
[48.]
J.W. Pape, B. Liautaud, F. Thomas, et al.
Characteristics of the acquired immunodeficiency syndrome (AIDS) in Haití.
N Engl J Med, 309 (1983), pp. 945-950
[49.]
A.E. Pitchenik, B.W. Russell, T. Cleary, I. Pejovic, C. Cole, D.E. Snider.
The prevalence of tuberculosis and drug resistance among haitians.
N Engl J Med, 307 (1982), pp. 162-165
[50.]
S. Maayan, G.P. Wormser, D. Hewlett, et al.
Acquired immunodeficiency syndrome (AIDS) in an economically disadvantaged population.
Arch Intern Med, 145 (1985), pp. 1607-1612
[51.]
SIDA.
Síndrome de la inmunodeficiencia adquirida.
Situación actual. Información Terapéutica de la Seguridad Social, vol10 (1986),
Copyright © 1988. Sociedad Española de Neumología y Cirugía Torácica
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