TY - JOUR T1 - Relationship of Muscle Mass Determined by DEXA with Spirometric Results in Healthy Individuals JO - Archivos de Bronconeumología T2 - AU - Martín Holguera,Rafael AU - Turrión Nieves,Ana Isabel AU - Rodríguez Torres,Rosa AU - Alonso,María Concepción SN - 15792129 M3 - 10.1016/j.arbr.2017.05.006 DO - 10.1016/j.arbr.2017.05.006 UR - https://www.archbronconeumol.org/en-relationship-muscle-mass-determined-by-articulo-S1579212917301751 AB - IntroductionMuscle mass maybe a determining factor in the variability of spirometry results in individuals of the same sex and age who have similar anthropometric characteristics. The aim of this study was to determine the association between spirometric results from healthy individuals and their muscle mass assessed by dual energy X-ray absorptiometry (DEXA). MethodsA sample of 161 women and 144 men, all healthy non-smokers, was studied. Ages ranged from18 to77years. For each subject, spirometry results and total and regional lean mass values obtained by full body DEXA were recorded. A descriptive analysis of the variables and a regression analysis were performed to study the relationship between spirometric variables and lean body mass, correcting for age and body mass index (BMI). ResultsIn both sexes all muscle mass variables correlated positively and significantly with spirometric variables, and to a greater extent in men. After partial adjustment of correlations by age and BMI, the factor which best explains the spirometric variables is the total lean body mass in men, and trunk lean body mass in women. ConclusionsIn men, muscle mass in the lower extremities is most closely associated with spirometric results. In women, it is the muscle mass of the trunk. In both sexes muscle mass mainly affects FEV1. ER -