TY - JOUR T1 - Consensus Document on Prevention and Treatment of Tuberculosis in Patients for Biological Treatment JO - Archivos de Bronconeumología T2 - AU - Mir Viladrich,Isabel AU - Daudén Tello,Esteban AU - Solano-López,Guillermo AU - López Longo,Francisco Javier AU - Taxonera Samso,Carlos AU - Sánchez Martínez,Paquita AU - Martínez Lacasa,Xavier AU - García Gasalla,Mercedes AU - Dorca Sargatal,Jordi AU - Arias-Guillén,Miguel AU - García García,José Maria SN - 15792129 M3 - 10.1016/j.arbr.2015.11.005 DO - 10.1016/j.arbr.2015.11.005 UR - https://www.archbronconeumol.org/en-consensus-document-on-prevention-treatment-articulo-S1579212915003547 AB - Tuberculosis risk is increased in patients with chronic inflammatory diseases receiving any immunosuppressive treatment, notably tumor necrosis factor (TNF) antagonists therapy. Screening for the presence of latent infection with Mycobacterium tuberculosis and targeted preventive treatment to reduce the risk of progression to tuberculosis disease is mandatory in these patients.This Consensus Document summarizes the current knowledge and expert opinion of biologic therapies, including TNF-blocking treatments. It provides recommendations for the use of interferon-gamma release assays (IGRA) and tuberculin skin test (TST) for the diagnosis of latent tuberculosis infection in these patients, and for the type and duration of preventive therapy. ER -