TY - JOUR T1 - Morbidity and Mortality in Octogenarians With Lung Cancer Undergoing Pneumonectomy JO - Archivos de Bronconeumología T2 - AU - Rodríguez,María AU - Gómez Hernández,María Teresa AU - Novoa,Nuria M. AU - Aranda,José Luis AU - Jiménez,Marcelo F. AU - Varela,Gonzalo SN - 15792129 M3 - 10.1016/j.arbr.2015.03.007 DO - 10.1016/j.arbr.2015.03.007 UR - https://www.archbronconeumol.org/en-morbidity-mortality-in-octogenarians-with-articulo-S1579212915000725 AB - ObjectiveEvaluate the restrictiveness of selection criteria for lung resection in lung cancer patients over 80 years of age compared to those applied in younger patients. Compare and analyze 30-day mortality and postoperative complications in both groups of patients. MethodsCase-controlled retrospective analysis. Study populationConsecutive patients undergoing elective anatomical lung resection. Population was divided into octogenarians (cases) and younger patients (controls). Variables determining surgical risk (BMI, FEV1%, postoperative FEV1%, FEV1/FVC, DLCO and pneumonectomy rate) were compared using either Wilcoxon or Chi-squared tests. Thirty-day mortality and morbidity odds ratio were calculated. A logistic regression model with bootstrap resampling was constructed, including postoperative complications as dependent variable and age and post-operative FEV1% as independent variables. Data were retrieved from a prospective database. ResultsNo statistically significant differences were found in BMI (P=.40), FEV1% (P=.41), postoperative FEV1% (P=.23), FEV1/FVC (P=.23), DLCO (P=.76) and pneumonectomy rate (P=.90). Case mortality was 1.85% and control mortality was 1.26% (OR: 1.48). Cardiorespiratory complications occurred in 12.80% of younger subjects and in 13.21% of patients aged 80 years or older. (OR: 1.03). In the logistic regression, only FEV1% was related to postoperative complications (P<.005). ConclusionSelection criteria for octogenarians are similar to those applied in the rest of the population. Advanced age is not a factor for increased 30-day mortality or postoperative morbidity. ER -