Archivos de Bronconeumología

ISSN: 0300-2896

Archivos de Bronconeumologia is an international journal that publishes original studies whose content is based upon results of research initiatives dealing with several aspects of respiratory medicine including epidemiology, respiratory physiology, pathophysiology of respiratory diseases, clinical management, thoracic surgery, pediatric lung diseases, respiratory critical care, respiratory allergy and translational research. Other types of articles such as editorials, reviews, and different types of letters are also published in the journal. Additionally, the journal expresses the voice of the following scientific societies: the Spanish Respiratory Society of Pneumology and Thoracic Surgery (SEPAR; https://www.separ.es/), the Latin American Thoracic Society (ALAT; https://alatorax.org/), and the Iberian American Association of Thoracic Surgery (AIACT; http://www.aiatorax.com/).

It is a monthly journal in which all manuscripts are sent to peer-review and handled by the editor or an associate editor from the team and the final decision is made on the basis of the comments from the expert reviewers and the editors. The journal is published solely in English. All the published data is composed of novel manuscripts not previously published in any other journal and not being in consideration for publication in any other journal..

The journal is indexed at Science Citation Index Expanded, Medline/Pubmed, Embase and SCOPUS. Access to any published article is possible through the journal's web page as well as from Pubmed, ScienceDirect, and other international databases. Furthermore, the journal is also present in X, Facebook and Linkedin. Manuscripts can be submitted electronically using the following web site: https://www.editorialmanager.com/ARBR/.

Indexed in:

Medline, Science Citation Index Expanded (SCIE)

Abstract
Keywords
Resumen
Palabras clave
Introduction
Material and methods
Study design
Study population and icu data collection
Follow-up at 3, 6, and 12 months
Blood samples
Biomarkers
Quantification of microrna
Data management
Automated analysis and sub-studies
Data quality
Results
Study population and icu data
Follow-up at 3, 6, and 12 months
Blood samples
Biomarkers
Quantification of microrna
Data management
Data quality
Discussion
Epidemiological study
Blood sample testing
Follow-up studies
Data and quality management
Conclusions
Funding
Authors’ contributions
Conflict of interests
Acknowledgments
Bibliography

Original

DOI: 10.1016/j.arbres.2022.03.010

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Methodology of a Large Multicenter Observational Study of Patients with COVID-19 in Spanish Intensive Care Units

Metodología de un gran estudio observacional multicéntrico de pacientes con COVID-19 en unidades de cuidados intensivos en España

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Antoni Torresa,b,

, Anna Motosa,b, Adrián Ceccatoa,b, Jesús Bermejo-Martina,c,d, David de Gonzalo-Calvoa,h, Raquel Pérezf, Marta Barrosof, Ion Zubizarreta Pascualai, Jessica Gonzaleza,b,c,d,e,f,g,h, Laia Fernández-Barata,b, Ricard Ferrere, Jordi Rierae, Dario García-Gasullaf, Oscar Peñuelasa,g, José Ángel Lorentea,g, Raquel Almansac, Rosario Menéndezi, Kasra Kiarostamib, Joan Cansecoa,b, Rosario Amaya Villarj..., José M. Añóna,k, Ana Balan Mariñol, Carme Barberàm, José Barberánn, Aaron Blandino Ortizo, Maria Victoria Boadoah, Elena Bustamante-Munguirap, Jesús Caballeroq, María Luisa Cantón-Bulnesr, Cristina Carbajales Pérezs, Nieves Carbonellt, Mercedes Catalán-Gonzálezu, Raúl de Frutosv, Nieves Francow, Cristóbal Galbánx, Víctor D. Gumucio-Sanguinoy, María del Carmen de la Torrez, Emili Díazaa, Ángel Estellabb, Elena Gallegocc, José Luis García Garmendiadd, José M. Gómezee, Arturo Huertaff, Ruth Noemí Jorge Garcíagg, Ana Loza-Vázquezhh, Judith Marin-Corralii, María Cruz Martin Delgadojj, Amalia Martínez de la Gándarakk, Ignacio Martínez Varelall, Juan López Messamm, Guillermo M. Albaicetaa,nn, Maite Nietooo, Mariana Andrea Novopp, Yhivian Peñascoqq, Felipe Pérez-Garcíarr, Juan Carlos Pozo-Laderasss, Pilar Ricarttt, Víctor Sagredouu, Ángel Sánchez-Mirallesvv, Susana Sancho Chinestaww, Mireia Serra-Fortunyxx, Lorenzo Sociasyy, Jordi Solé-Violanzz, Fernando Suárez-Sipmannab, Luis Tamayo Lomasac, José Trenadoad, Alejandro Úbedaae, Luis Jorge Valdiviaaf, Pablo Vidalag, Ferran Barbéa,h, on behalf of CIBERESUCICOVID Project (COV20/00110, ISCIII) Ver más

a CIBER de Enfermedades Respiratorias (CIBERES), Spain

b Department of Pneumology, Hospital Clínic of Barcelona, August Pi i Sunyer Biomedical Research Institute-IDIBAPS, University of Barcelona, Barcelona, Spain

c Group for Biomedical Research in Sepsis (BioSepsis), Instituto de Investigación Biomédica de Salamanca (IBSAL), Salamanca, Spain

d Hospital Universitario Río Hortega de Valladolid, Valladolid, Spain

e Intensive Care Department, Hospital Universitari Vall d’Hebron, Vall d’Hebron Institut de Recerca, Barcelona, Spain

f Barcelona Supercomputing Centre (BSC), Barcelona, Spain

g Hospital Universitario de Getafe, Universidad Europea, Madrid, Spain

h Translational Research in Respiratory Medicine, Respiratory Department, Hospital Universitari Arnau de Vilanova and Santa Maria, IRBLleida, Lleida, Spain

i Pulmonary Department, University and Polytechnic Hospital La Fe, Valencia, Spain

j Intensive Care Clinical Unit, Hospital Universitario Virgen de Rocío, Sevilla, Spain

k Servicio de Medicina Intensiva, Hospital Universitario La Paz, IdiPAZ, Madrid, Spain

l Hospital Universitario San Agustín, Avilés, Asturias, Spain

m Hospital Santa Maria, IRBLleida, Lleida, Spain

n Hospital Universitario HM Montepríncipe, Universidad San Pablo-CEU, Madrid, Spain

o Servicio de Medicina Intensiva, Hospital Universitario Ramón y Cajal, Madrid, Spain

p Department of Intensive Care Medicine, Hospital Clínico Universitario de Valladolid, Valladolid, Spain

q Critical Care Department, Hospital Universitari Arnau de Vilanova, IRBLleida, Lleida, Spain

r Intensive Care Clinical Unit, Hospital Universitario Virgen Macarena, Sevilla, Spain

s Intensive Care Unit, Hospital Álvaro Cunqueiro, Vigo, Pontevedra, Spain

t Intensive Care Unit, Hospital Clínico y Universitario de Valencia, Valencia, Spain

u Department of Intensive Care Medicine, Hospital Universitario 12 de Octubre, Madrid, Spain

v Servicio de Anestesiología y Reanimación, Hospital Universitario de Basurto, Bilbao, Vizcaya, Spain

w Hospital Universitario de Móstoles, Madrid, Spain

x Department of Medicine, CHUS, Complejo Hospitalario Universitario de Santiago, Santiago de Compostela, A Coruña, Spain

y Department of Intensive Care, Hospital Universitari de Bellvitge, Bellvitge Biomedical Research Institute (IDIBELL), L’Hospitalet de Llobregat, Barcelona, Spain

z Hospital de Mataró, Barcelona, Spain

aa Critical Care Department, Corporació Sanitària Parc Taulí, Department of Medicine, Universitat Autònoma de Barcelona (UAB), Sabadell, Barcelona, Spain

bb Departamento de Medicina, Facultad de Medicina, Universidad de Cádiz, Hospital Universitario de Jerez, Jerez de la Frontera, Cádiz, Spain

cc Unidad de Cuidados Intensivos, Hospital Universitario San Pedro de Alcántara, Cáceres, Spain

dd Intensive Care Unit, Hospital San Juan de Dios del Aljarafe, Bormujos, Sevilla, Spain

ee Hospital General Universitario Gregorio Marañón, Madrid, Spain

ff Pulmonary and Critical Care Division, Emergency Department, Clínica Sagrada Família, Barcelona, Spain

gg Intensive Care Department, Hospital Nuestra Señora de Gracia, Zaragoza, Spain

hh Unidad de Medicina Intensiva, Hospital Universitario Virgen de Valme, Sevilla, Spain

ii Critical Care Department, Hospital del Mar-IMIM, Barcelona, Spain

jj Hospital Universitario de Torrejón-Universidad Francisco de Vitoria, Madrid, Spain

kk Department of Intensive Medicine, Hospital Universitario Infanta Leonor, Madrid, Spain

ll Critical Care Department, Hospital Universitario Lucus Augusti, Lugo, Spain

mm Complejo Asistencial Universitario de Palencia, Palencia, Spain

nn Departamento de Biología Funcional, Instituto Universitario de Oncología del Principado de Asturias, Universidad de Oviedo, Instituto de Investigación Sanitaria del Principado de Asturias, Hospital Central de Asturias, Oviedo, Asturias, Spain

oo Hospital Universitario de Segovia, Segovia, Spain

pp Servei de Medicina Intensiva, Hospital Universitari Son Espases, Palma de Mallorca, Illes Balears, Spain

qq Servicio de Medicina Intensiva, Hospital Universitario Marqués de Valdecilla, Santander, Cantabria, Spain

rr Servicio de Microbiología Clínica, Hospital Universitario Príncipe de Asturias, Departamento de Biomedicina y Biotecnología, Universidad de Alcalá de Henares, Madrid, Spain

ss UGC-Medicina Intensiva, Hospital Universitario Reina Sofía, Instituto Maimónides IMIBIC, Córdoba, Spain

tt Servei de Medicina Intensiva, Hospital Universitari Germans Trias, Badalona, Barcelona, Spain

uu Hospital Universitario de Salamanca, Salamanca, Spain

vv Hospital de Sant Joan d’Alacant, Sant Joan d’Alacant, Alacant, Spain

ww Servicio de Medicina Intensiva, Hospital Universitario y Politécnico La Fe, Valencia, Spain

xx Pneumology Department, Hospital Verge de la Cinta, Tortosa, Tarragona, Spain

yy Intensive Care Unit, Hospital Son Llàtzer, Palma de Mallorca, Illes Balears, Spain

zz Critical Care Department, Hospital de Gran Canaria Dr. Negrín, Las Palmas, Spain

ab Intensive Care Unit, Hospital Universitario de La Princesa, Madrid, Spain

ac Critical Care Department, Hospital Universitario Río Hortega de Valladolid, Valladolid, Spain

ad Servicio de Medicina Intensiva, Hospital Universitario Mútua de Terrassa, Terrassa, Barcelona, Spain

ae Servicio de Medicina Intensiva, Hospital Punta de Europa, Algeciras, Cádiz, Spain

af Hospital Universitario de León, León, Spain

ag Complexo Hospitalario Universitario de Ourense, Ourense, Spain

ah Hospital Universitario de Cruces, Barakaldo, Vizcaya, Spain

ai Ubikare Technology, Vizcaya, Spain

Article

This article is available in English

Methodology of a Large Multicenter Observational Study of Patients with COVID-19 in Spanish Intensive Care Units

Antoni Torres, Anna Motos, Adrián Ceccato, Jesús Bermejo-Martin, David de Gonzalo-Calvo, Raquel Pérez, Marta Barroso, Ion Zubizarreta Pascual, Jessica Gonzalez, Laia Fernández-Barat, Ricard Ferrer, Jordi Riera, Dario García-Gasulla, Oscar Peñuelas, José Ángel Lorente, Raquel Almansa, Rosario Menéndez, Kasra Kiarostami, Joan Canseco, Rosario Amaya Villar, José M. Añón, Ana Balan Mariño, Carme Barberà, José Barberán, Aaron Blandino Ortiz, Maria Victoria Boado, Elena Bustamante-Munguira, Jesús Caballero, María Luisa Cantón-Bulnes, Cristina Carbajales Pérez, Nieves Carbonell, Mercedes Catalán-González, Raúl de Frutos, Nieves Franco, Cristóbal Galbán, Víctor D. Gumucio-Sanguino, María del Carmen de la Torre, Emili Díaz, Ángel Estella, Elena Gallego, José Luis García Garmendia, José M. Gómez, Arturo Huerta, Ruth Noemí Jorge García, Ana Loza-Vázquez, Judith Marin-Corral, María Cruz Martin Delgado, Amalia Martínez de la Gándara, Ignacio Martínez Varela, Juan López Messa, Guillermo M. Albaiceta, Maite Nieto, Mariana Andrea Novo, Yhivian Peñasco, Felipe Pérez-García, Juan Carlos Pozo-Laderas, Pilar Ricart, Víctor Sagredo, Ángel Sánchez-Miralles, Susana Sancho Chinesta, Mireia Serra-Fortuny, Lorenzo Socias, Jordi Solé-Violan, Fernando Suárez-Sipmann, Luis Tamayo Lomas, José Trenado, Alejandro Úbeda, Luis Jorge Valdivia, Pablo Vidal, Ferran Barbé

10.1016/j.arbres.2022.03.010

Arch Bronconeumol. 2022;58 Supl 1:22-31