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Vol. 22. Issue 2.
Pages 65-70 (March - April 1986)
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Vol. 22. Issue 2.
Pages 65-70 (March - April 1986)
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Nodulo pulmonar solitario II. Estudio diagnostico mediante analisis discriminante multifactorial
Solitary pulmonary nodule II. Diagnostic study with multifactorial discriminating analysis
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A. Salvatierra Velazquez*, A. Vazquez Muñiz**, J. Lopez Pujol*, F. Sebastian Quetglas*, M. Velasco Garcia***, A. Cueto Ladron de Guevara****, J. Candelas Barrios****, F. Garrido Garcia***
* Servicio de Cirugía Torácica. Hospital Reina Sofía. Córdoba
** Centro de Investigación de IBM-Universidad Autónoma de Madrid
*** Cátedra de Patología Qurúrgica. Facultad de Medicina de Cádiz
**** Servicio de Cirugía Torácica. Hospital Ramón y Cajal. Madrid
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Utilizando como muestra de entrenamiento 100 nódulos pulmonares solitarios (NPS) y sometiendo los datos obtenidos de la estimación de 30 caraderísticas derivadas de pruebas diagnósticas sendllas e incruentas, a un proceso de cálculo de funciones discriminantes por programadón lineal, ha sido factible encontrar fronteras óptimas a efectos de diagnóstico tanto entre nodulos benignos y maligmos, como entre los distintos grupos nosológicos entre sí. Para comprobar la eficacia de las reglas dasificatorias desarrolladas, éstas han sido aplicadas a un nuevo grupo de 32 NPS, resultando una tasa de asignaciones corredas del 96,9% entre las opdones de benignidad/malignidad (IC: 82,6% — 99,9%; p < 0,05) y del 75% en la clasificadón de un nodulo problema en una entidad nosológica concreta (IC: 54,1% — 87,7%; p < 0,05). El método puede ser útil como ayuda al clínico en la toma de decisión de conduda frente a un NPS problema.

By taking 100 solitary pulmonary nodules (SPN), as a sample and using the data obtained by estimating 30 characteristics derived from simple and invasive diagnostic methods for calculus of the discriminating fundions of a lineal program, the optimal borders for diagnosis of both benign and malignant nodules could be established as well as the dividing lines between the different nosological groups themselves.

To test the efficacy of the developed dassifications, they were applied to a new group of 32 SPNs, resulting in a correct classification in 96,9%, of the options benign/malignant (IC: 82,6 — 99,9%; p < 0,05) and in 75% of those classified as problematic nodules of certain nosology (IC: 54,1 — 87,7%; p < 0,05). The method may be a useful aid for the clinician when dedding how to manage SPN.

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Copyright © 1986. Sociedad Española de Neumología y Cirugía Torácica
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