Article information
Se analizan las características clínicas y paraclínicas de una serie de 100 nódulos pulmonares solitarios (NPS) intervenidos quirúrgicamente tras la aplicación de un protocolo de estudio. Se obtuvo un diagnóstico preoperatorio de sospecha o certeza en el 86,4% de las neoplasias malignas (44 casos), resultando el aspirado, cepillado y biopsia bronquiales, biopsia transbronquial y punción aspirativa transtorácica, técnicas complementarias entre sí. Sólo el 7,1% de los nódulos de naturaleza benigna (56) pudieron ser diagnosticados preoperatoriamente. La toracotomía, con una mortalidad nula y una tasa de complicaciones del 13%, permitió la resección presuntamente curativa del 100% de los NPS que resultaron ser tumores malignos primitivos, alcanzándose una supervivencia del 66,2% a los 46 meses.
The authors analyze the clinical and paraclinical characteristics of a series of 100 solitary pulmonary nodules (S.P.N.) treated surgically after application of a study protocol. A preoperatory suspected or firm diagnosis was obtained in 86,4% of all malignant neoplasias (44 cases), with apiration, brushing and bronchial or transbronchial biopsy and transthoracic aspiration puncture used as diagnostic methods complementing each other. Preoperatory diagnoses could be established in only 7,1% of all benign nodules (56 cases).
Thoracotomy, without mortality and a 13% complications rate, allowed resection considered as curative in 100% of primary malignant tumors with a survival rate of 66,2% after 46 months.
Full text is only aviable in PDF
Bibliografia
[1.]
D.A. Cortese.
Solitary pulmonary nodule; observe, operate, or what?.
Chest, 81 (1982), pp. 662-664
[2.]
J. Meyer Th.
The solitary pulmonary nodule. An aggressive workup.
Postgrad Med, 73 (1983), pp. 66-75
[3.]
P. Martin Escribano, J. Alfaro Abreu.
Nódulo pulmonar solitario.
Med Clin, 81 (1983), pp. 914-919
[4.]
B.R. Walske.
The solitary pulmonary nodule. A review of 217 cases.
Dis Chest, 49 (1966), pp. 302-304
[5.]
E.W. Davis, J.W. Peabody, S. Katz.
The solitary pulmonary nodule. A ten-year study based on 215 cases.
J Thorac Surg, 32 (1956), pp. 728-771
[6.]
J. Steele, W. Kleitsch, J. Dunn, P. Buell.
Survival in males with bronchogenic carcinoma resected as asymptomatic solitary pulmonary nodule.
Ann Thorac Cardiovasc Surg, 2 (1966), pp. 368-376
[7.]
R.J. Jackman, C.A. Good, O.T. Clagget, L.B. Woolner.
Survival rates in peripheral bronchogenic carcinomas up to four centimeters in diameters presenting as solitary pulmonary nodules.
J Thorac Cardiovasc Surg, 57 (1969), pp. 1-8
[8.]
H. Toomes, A. Delphendahl, H.-G. Manke, I. Vogt-Moykopf.
The coin lesion of the lung. A review of 955 resected coin lesions.
Cancer, 51 (1983), pp. 534-537
[9.]
G.A. Higgins, T.W. Shields, R.J. Kheehn.
The solitary pulmonary nodule: ten-year follow-up of Veterans Administration Armed Forces cooperative study.
Arch Surg, 110 (1975), pp. 570-575
[10.]
S.M. Holin, R.E. Dwork, S. Glaser, A.E. Rikli, J.B. Stocklen.
Solitary pulmonary nodules found in a community-wide chest roentegenographic survey. A five-year follow-up study.
Am Rev Tuberc, 79 (1959), pp. 427-439
[11.]
C.D. McClure, K.R. Boucot, G.A. Shipman, A.G. Guilliam, B.K. Milmore, J.W. Lloyd.
The solitary pulmonary nodule and primary lung malignancy.
Arch Environ Health, 3 (1961), pp. 127-139
[12.]
G.W. Comstock, R.H. Vaughan, G. Montgomery.
Outcome of solitary pulmonary nodules discovered in a x-ray screening program.
N Engl J Med, 254 (1956), pp. 1018-1024
[13.]
R.R. Taylor, L.N. Rivkin, J.M. Salyer.
The solitary pulmonary nodule. A review of 236 consecutive cases 1944 to 1959.
Ann Surg, 147 (1958), pp. 197-202
[14.]
G. Trunk, D.R. Gracey, R.B. Byrd.
The management and evaluation of the solitary pulmonary Nodule.
Chest, 66 (1974), pp. 236-239
[15.]
J. Berkson.
Limitations of the aplication of fourfold table analysis to hospital date.
Biometries Bull, 2 (1946), pp. 47-51
[17.]
E.E. Clifton, B.B.A. Irani.
Pulmonary tuberculosis and cancer.
N Y State J Med, 70 (1970), pp. 274-278
[18.]
P. Gopalakrishnan, J.E. Miller, J.S. McLauhlin.
Pulmonary tuberculosis and coexisting carcinoma. A 10-year experience and review of the literature.
Am Surg, 41 (1975), pp. 405-408
[19.]
J.M. Carey, A.E. Greer.
Bronchogenic carcinoma complicating pulmonary tuberculosis. A report of 8 cases and a review of 140 cases since 1932.
Ann Intern Med, 49 (1958), pp. 161-180
[20.]
R. Steinitz.
Pulmonary tuberculosis and carcinoma of the lung. A survey from two population-based disease registers.
Am Rev Respir Dis, 92 (1965), pp. 758-766
[21.]
L.J. Fontenelle, D. Campbell.
Coexisting bronchogenic carcinoma and pulmonary tuberculosis.
Ann Thorac Surg, 9 (1970), pp. 431-435
[22.]
W.G. Cahan, J.P. Shah, E.B. Castro.
Benign solitary lung lesions in patients with cancer.
Ann Surg, 187 (1978), pp. 241-244
[23.]
F. Saegesser.
Traitement chirurgical des foyers ronds pulmonaires décelés chez un cancéreux et huit cancéreuses du sein Métastase solitaire?. Deuxieme cancer primaire bronchopulmonaire?. Foyer rond de nature bénigne?.
Sem Hóp Paris, 56 (1980), pp. 231-237
[24.]
J.P. Neifeld, L.L. Michaelis, J.L. Doppman.
Suspected pulmonary metastases. Correlation of chest-x-ray, whole lung tomography and operative findings.
Cancer, 39 (1977), pp. 383-387
[25.]
P. Laval, J.P. Kleisbauer, A. Bettendorf, J. Colonna, R. Poirier.
Carcinomes bronchiques primitives.
Epidémiologie. Encyclopedie Medico-Chirurgicale. Paris, (1980), pp. 6022
[26.]
L.F. Meisner, E. Gilbert, H.W. Ris, G. Haverty.
Genetic mechanisms in cancer predisposition. Report of a cancer family.
Cancer, 43 (1979), pp. 679-689
[27.]
G. Tokuhata, A. Lilienfeld.
Familial aggregation of lung cancer in humans.
J Natl Cancer Inst, 30 (1963), pp. 289-298
[28.]
J.D. Steele.
The solitary pulmonary nodule Report of a cooperative study of resected asymptomatic solitary pulmonary nodules in males.
J Thorac Cardiovasc Surg, 46 (1963), pp. 21-39
[29.]
J. Zapatero, J.M. Bellon, C. Baamonde, et al.
Hamartomas pulmonares.
Rev Esp Cir CTV, 3 (1982), pp. 180-186
[30.]
S.S. Siegelman, E.A. Zerhouni, F.P. Leo, N.F. Khouri, F.P. Stitik.
CT of the solitary pulmonary nodule.
AJR, 135 (1980), pp. 1-13
[31.]
J.K. Siemsen, S.F. Grebe, A.D. Vaxman.
The use of Gallium-67 in pumonary disorders.
Semin Nucl Med, 8 (1978), pp. 235-249
[32.]
C.D. Teates, S.T. Bray, B.R.J. Williamson.
Tumor detection with67 Ga-citrate: a literature survey (1970-1978).
Clin Nucl Med, 12 (1978), pp. 456-460
[33.]
A.D. Vaxman, P.J. Julien, M.B. Brachman, et al.
Gallium scintigraphy in bronchogenic carcinoma. The efect of tumor location on sensivity and specificity.
Chest, 86 (1984), pp. 178-183
[34.]
J.M. Ales Reinlein, F. Fernandez Lozano, E. Soriano García.
Diagnóstico inmunológico de la hidatidosis.
Rev Clin Esp, 149 (1978), pp. 353-356
[35.]
M. Aubert, P. Viard.
Etude stadistique sur l‘hydatidose pleuro-pulmonaire dans le bassin mediterranéen en 1982. A propos de 8.384 cas.
Ann Chir Thorac Cardio-vasc, 37 (1983), pp. 74-77
[36.]
A.B. Kheder, L. El Mekki, M.F. Hamza, M. Jeguirim, R. El Gharbi.
Les aspects epidémiologiques, cliniques, radiologiques et inmunologiques du kyste hydatique pulmonaire en Tunisie.
Ann Chir Thorac Cardio-vasc, 37 (1983), pp. 82-83
[37.]
J.M. Wallace, A.L. Deutsch.
Flexible fiberoptic bronchoscopy and percutaneous needle lung aspiration for evaluating the solitary pulmonary nodule.
Chest, 81 (1982), pp. 665-671
[38.]
J.B. Mark, S.I. Marglin, R.A. Castellino.
The role of bronchoscopy and needle aspiration in the diagnosis of peripheral lung masses.
J Thorac Cardiovasc Surg, 76 (1978), pp. 266-268
[39.]
G.A. Lillington.
The solitary pulmonary nodule.
Am Rev Respir Dis, 110 (1974), pp. 699-707
[40.]
J.F. Ray, B.R. Lawton, G.E. Magnin, et al.
The coin lesion story: update 1976. Twenty years experience with early thoracotomy for 179 suspected malignant coin lesions.
Chest, 70 (1976), pp. 332-336
[41.]
T.M. O’Connor, D.J. Lepley, W. Weisel, R.R. Watson.
The malignant solitary pulmonary nodule follow-up study.
Arch Surg, 86 (1963), pp. 985-988
[42.]
J. Yashar, J.J. Yashar.
Factors affecting long-term survival of patients with bronchogenic carcinoma.
Am J Surg, 129 (1975), pp. 386-393
[43.]
R.H. Overholt, J.A. Bougas, F.M. Woods.
Surgical treatment of lung cancer found on x-ray survey.
N Engl J Med, 252 (1955), pp. 429-432
Copyright © 1986. Sociedad Española de Neumología y Cirugía Torácica
