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Vol. 30. Issue 4.
Pages 192-195 (April 1994)
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Vol. 30. Issue 4.
Pages 192-195 (April 1994)
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Neutrofilia en el lavado broncoalveolar de pacientes con sida y neumonía por Pneumocystis carinii. Consideraciones sobre su valor pronóstico en nuestro medio
Neutrophilia in the bronchoalveolar lavage of patients with AIDS and Pneumocystis carinii pneumonía. Reflections on its prognostic value in our context
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J. Gea, X. Aran, J.M. Broquetas
Servicios de Neumología. Hospital del Mar. Barcelona
J. Sauleda*,1, E. Gimferrer**, M. Conangla**
** Servicios de Anatomía Patológica. Hospital del Mar. Barcelona
* Servicio de Neumología. Hospital Son Dureta. Palma de Mallorca
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Se analiza el valor pronóstico en nuestro medio de la neutrofilia (> 5%) en el lavado broncoalveolar (LBA) de 21 pacientes con sida y neumonía por Pneumocystis carinii.

La neutrofilia no parece revelarse como un buen marcador pronóstico en nuestro entorno. Así hemos hallado que sólo el 33% de nuestra población tenía neutrofília, con una cifra media de 6 ± 4%. La sensibilidad de dicho parámetro respecto al riesgo de fallecer fue muy baja (25%), con una moderada especificidad (65%).

Contrastando con lo referido en algunos trabajos precedentes del ámbito anglosajón, la neutrofília en el LBA es probablemente de escasa utilidad pronostica en nuestro medio. Ello sería fruto de diversos factores, entre los que cabría destacar el tipo de población (en su mayoría adictos a drogas por vía parenteral, ADVP) y la modalidad terapéutica utilizada (tratamiento empírico y precoz).

The prognostic valué of neutrophilia (> 5%) in bronchoalveolar lavage (BAL) in our context is studied in 21 patients with AIDS and Pneumocystis carinii pneumonia.

Neutrophilia does not seem to be a good prognostic indicator in our context. We have found this condition, with a mean of 6 ± 4%, in only 33% of our sample. The sensitivity of this parameter with respect to risk of death was very low (25%), while specificity was moderate (65%).

In contrast with what has been reported in studies done with Anglo-Saxon populations, neutrophilia in BAL is probably of little prognostic use in our context. This may be due to various factors, among them the type of population (most being intravenous drug users) and the therapeutic protocol (early empirical treatment).

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Copyright © 1994. Sociedad Española de Neumología y Cirugía Torácica
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