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        "resumen" => "<span class="elsevierStyleSectionTitle">Objective</span><p class="elsevierStyleSimplePara elsevierViewall">TO study the incidence&#44; severity&#44; and mortality rates of pneumonia in a cohort of chronic obstructive pulmonary disease &#40;COPD&#41; patients monitored over 3 years&#46;</p> <span class="elsevierStyleSectionTitle">Patients and methods</span><p class="elsevierStyleSimplePara elsevierViewall">A total of 596 patients diagnosed with COPD according to spirometric criteria were included in the study&#46; The variables assessed were mortality and severity according to the Pneumonia Severity Index &#40;PSI&#41; for community-acquired pneumonia &#40;CAP&#41;&#46;</p> <span class="elsevierStyleSectionTitle">Results</span><p class="elsevierStyleSimplePara elsevierViewall">Of the 596 patients included in the study&#44; 75 &#40;12&#46;6&#37;&#41; developed at least 1 episode of pneumonia during the 3 years of the study&#46; The overall incidence of pneumonia was 55&#46;1 per 1000 person-years&#46; There were 88 episodes in 75 patients&#46; COPD severity&#44; evaluated based on percentage of predicted FEV<span class="elsevierStyleInf">1</span>&#44; was mild in 9 patients&#44; moderate in 24&#44; and severe in 42&#46; Seventy-six &#40;86&#46;3&#37;&#41; episodes were CAP and 12 &#40;13&#46;6&#37;&#41; were acquired in hospital&#46; Fourteen CAP cases corresponded to PSI group V&#44; 28 to group IV&#44; 20 to group III&#44; and 14 to groups I and II&#46; Overall mortality was 12&#46;5&#37; &#40;11&#47;88&#41;&#46; The mortality rate was 41&#46;7&#37; &#40;5&#47;12&#41; for nosocomial cases and 7&#46;8&#37; &#40;6&#47;76&#41; for CAP cases &#40;OR&#44; 6&#46;67&#59; 95&#37; confidence interval&#44; 1&#46;65-26&#46;93&#41;&#46; Assessing CAP mortality by level of severity&#44; we found that the mortality rate was 35&#46;7&#37; &#40;5&#47;14&#41; for group V and 3&#46;5&#37; &#40;1&#47;28&#41; for group IV&#46; No deaths occurred among patients in the other severity groups&#46;</p> <span class="elsevierStyleSectionTitle">Conclusions</span><p class="elsevierStyleSimplePara elsevierViewall">The incidence of pneumonia in COPD patients is high&#46; More than half the cases of CAP &#40;55&#46;2&#37;&#41; in our COPD patients were classified in PSI risk groups IV and V&#46;</p>"
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        "resumen" => "<span class="elsevierStyleSectionTitle">Objetivo</span><p class="elsevierStyleSimplePara elsevierViewall">Estudiar la incidencia&#44; gravedad y mortalidad de las neumon&#237;as ocurridas en una cohorte de pacientes con enfermedad pulmonar obstructiva cr&#243;nica &#40;EPOC&#41; seguidos durante 3 a&#241;os&#46;</p> <span class="elsevierStyleSectionTitle">Pacientes y m&#233;todos</span><p class="elsevierStyleSimplePara elsevierViewall">Se incluy&#243; en el estudio a 596 pacientes con diagn&#243;stico espirom&#233;trico de EPOC&#46; Los par&#225;-metros a evaluar fueron la mortalidad y la gravedad valora-da de acuerdo con el Pneumonia Severity Index &#40;PSI&#41; para la neumon&#237;a adquirida en la comunidad &#40;NAC&#41;&#46;</p> <span class="elsevierStyleSectionTitle">Resultados</span><p class="elsevierStyleSimplePara elsevierViewall">De 596 pacientes incluidos en el estudio&#44; 75 &#40;12&#44;6&#37;&#41; desarrollaron al menos un episodio de neumon&#237;a durante el seguimiento&#46; La incidencia global de neumon&#237;a fue de 55&#44;1 por 1&#46;000 personas-a&#241;o&#46; Hubo 88 episodios en 75 pacientes&#46; El grado de la EPOC&#44; valorado seg&#250;n el FEV<span class="elsevierStyleInf">1</span> como porcentaje del te&#243;rico&#44; era en 9 pacientes leve&#44; en 24 moderado y en 42 grave&#46; De los episodios de neumon&#237;a&#44; 76 &#40;86&#44;3&#37;&#41; fueron adquiridos en la comunidad y 12 &#40;13&#44;6&#37;&#41; en el hospital&#46; Al valorar la gravedad de la NAC&#44; 14 episodios correspond&#237;an al grupo V&#44; 28 al grupo IV&#44; 20 al grupo III y 14 a los grupos I y II&#46; La mortalidad global fue del 12&#44;5&#37; &#40;11&#47;88&#41;&#46; La mortalidad en las neumon&#237;as nosocomiales fue del 41&#44;7&#37; &#40;5&#47;12&#41; y la mortalidad en las NAC fue del 7&#44;8&#37; &#40;6&#47;76&#41; &#40;OR&#58; 6&#44;67&#59; intervalo de confianza del 95&#37;&#44; 1&#44;65-26&#44;93&#41;&#46; Al valorar la mortalidad en las NAC seg&#250;n la gravedad&#44; se encontr&#243; que la mortalidad en el grupo V fue de un 35&#44;7&#37; &#40;5&#47;14&#41;&#44; en el grupo IV del 3&#44;5&#37; &#40;1&#47;28&#41; y nula en el res-to de los grupos&#46;</p> <span class="elsevierStyleSectionTitle">Conclusiones</span><p class="elsevierStyleSimplePara elsevierViewall">Hay una elevada incidencia de neumon&#237;a en los pacientes con EPOC&#46; M&#225;s de la mitad de las NAC &#40;55&#44;2&#37;&#41; ocurridas en nuestros pacientes con EPOC est&#225;n dentro de los grupos de riesgo del PSI IV y V&#46;</p>"
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Original Articles
Prognosis in Patients With Pneumonia and Chronic Obstructive Pulmonary Disease
M. Merino-Sánchez
Corresponding author
mercedesmerino@terra.es
ialfageme@separ.es

Correspondence: Dra. M. Merino Sánchez. Servicio de Neumología. Hospital Universitario de Valme. Ctra. de Cádiz, s/n. 41014 Sevilla. España
, I. Alfageme-Michavila, N. Reyes-Núñez, J. Lima-Álvarez
Servicio de Neumología, Hospital Universitario de Valme, Sevilla, Spain
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        "resumen" => "<span class="elsevierStyleSectionTitle">Objective</span><p class="elsevierStyleSimplePara elsevierViewall">TO study the incidence&#44; severity&#44; and mortality rates of pneumonia in a cohort of chronic obstructive pulmonary disease &#40;COPD&#41; patients monitored over 3 years&#46;</p> <span class="elsevierStyleSectionTitle">Patients and methods</span><p class="elsevierStyleSimplePara elsevierViewall">A total of 596 patients diagnosed with COPD according to spirometric criteria were included in the study&#46; The variables assessed were mortality and severity according to the Pneumonia Severity Index &#40;PSI&#41; for community-acquired pneumonia &#40;CAP&#41;&#46;</p> <span class="elsevierStyleSectionTitle">Results</span><p class="elsevierStyleSimplePara elsevierViewall">Of the 596 patients included in the study&#44; 75 &#40;12&#46;6&#37;&#41; developed at least 1 episode of pneumonia during the 3 years of the study&#46; The overall incidence of pneumonia was 55&#46;1 per 1000 person-years&#46; There were 88 episodes in 75 patients&#46; COPD severity&#44; evaluated based on percentage of predicted FEV<span class="elsevierStyleInf">1</span>&#44; was mild in 9 patients&#44; moderate in 24&#44; and severe in 42&#46; Seventy-six &#40;86&#46;3&#37;&#41; episodes were CAP and 12 &#40;13&#46;6&#37;&#41; were acquired in hospital&#46; Fourteen CAP cases corresponded to PSI group V&#44; 28 to group IV&#44; 20 to group III&#44; and 14 to groups I and II&#46; Overall mortality was 12&#46;5&#37; &#40;11&#47;88&#41;&#46; The mortality rate was 41&#46;7&#37; &#40;5&#47;12&#41; for nosocomial cases and 7&#46;8&#37; &#40;6&#47;76&#41; for CAP cases &#40;OR&#44; 6&#46;67&#59; 95&#37; confidence interval&#44; 1&#46;65-26&#46;93&#41;&#46; Assessing CAP mortality by level of severity&#44; we found that the mortality rate was 35&#46;7&#37; &#40;5&#47;14&#41; for group V and 3&#46;5&#37; &#40;1&#47;28&#41; for group IV&#46; No deaths occurred among patients in the other severity groups&#46;</p> <span class="elsevierStyleSectionTitle">Conclusions</span><p class="elsevierStyleSimplePara elsevierViewall">The incidence of pneumonia in COPD patients is high&#46; More than half the cases of CAP &#40;55&#46;2&#37;&#41; in our COPD patients were classified in PSI risk groups IV and V&#46;</p>"
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        "resumen" => "<span class="elsevierStyleSectionTitle">Objetivo</span><p class="elsevierStyleSimplePara elsevierViewall">Estudiar la incidencia&#44; gravedad y mortalidad de las neumon&#237;as ocurridas en una cohorte de pacientes con enfermedad pulmonar obstructiva cr&#243;nica &#40;EPOC&#41; seguidos durante 3 a&#241;os&#46;</p> <span class="elsevierStyleSectionTitle">Pacientes y m&#233;todos</span><p class="elsevierStyleSimplePara elsevierViewall">Se incluy&#243; en el estudio a 596 pacientes con diagn&#243;stico espirom&#233;trico de EPOC&#46; Los par&#225;-metros a evaluar fueron la mortalidad y la gravedad valora-da de acuerdo con el Pneumonia Severity Index &#40;PSI&#41; para la neumon&#237;a adquirida en la comunidad &#40;NAC&#41;&#46;</p> <span class="elsevierStyleSectionTitle">Resultados</span><p class="elsevierStyleSimplePara elsevierViewall">De 596 pacientes incluidos en el estudio&#44; 75 &#40;12&#44;6&#37;&#41; desarrollaron al menos un episodio de neumon&#237;a durante el seguimiento&#46; La incidencia global de neumon&#237;a fue de 55&#44;1 por 1&#46;000 personas-a&#241;o&#46; Hubo 88 episodios en 75 pacientes&#46; El grado de la EPOC&#44; valorado seg&#250;n el FEV<span class="elsevierStyleInf">1</span> como porcentaje del te&#243;rico&#44; era en 9 pacientes leve&#44; en 24 moderado y en 42 grave&#46; De los episodios de neumon&#237;a&#44; 76 &#40;86&#44;3&#37;&#41; fueron adquiridos en la comunidad y 12 &#40;13&#44;6&#37;&#41; en el hospital&#46; Al valorar la gravedad de la NAC&#44; 14 episodios correspond&#237;an al grupo V&#44; 28 al grupo IV&#44; 20 al grupo III y 14 a los grupos I y II&#46; La mortalidad global fue del 12&#44;5&#37; &#40;11&#47;88&#41;&#46; La mortalidad en las neumon&#237;as nosocomiales fue del 41&#44;7&#37; &#40;5&#47;12&#41; y la mortalidad en las NAC fue del 7&#44;8&#37; &#40;6&#47;76&#41; &#40;OR&#58; 6&#44;67&#59; intervalo de confianza del 95&#37;&#44; 1&#44;65-26&#44;93&#41;&#46; Al valorar la mortalidad en las NAC seg&#250;n la gravedad&#44; se encontr&#243; que la mortalidad en el grupo V fue de un 35&#44;7&#37; &#40;5&#47;14&#41;&#44; en el grupo IV del 3&#44;5&#37; &#40;1&#47;28&#41; y nula en el res-to de los grupos&#46;</p> <span class="elsevierStyleSectionTitle">Conclusiones</span><p class="elsevierStyleSimplePara elsevierViewall">Hay una elevada incidencia de neumon&#237;a en los pacientes con EPOC&#46; M&#225;s de la mitad de las NAC &#40;55&#44;2&#37;&#41; ocurridas en nuestros pacientes con EPOC est&#225;n dentro de los grupos de riesgo del PSI IV y V&#46;</p>"
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ISSN: 15792129
Original language: English
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2022 May 11 34 45
2022 April 17 25 42
2022 March 17 28 45
2022 February 14 23 37
2022 January 12 34 46
2021 December 19 44 63
2021 November 14 44 58
2021 October 19 36 55
2021 September 22 50 72
2021 August 12 21 33
2021 July 10 27 37
2021 June 9 21 30
2021 May 12 27 39
2021 April 27 44 71
2021 March 23 24 47
2021 February 10 22 32
2021 January 5 14 19
2020 December 9 13 22
2020 November 11 10 21
2020 October 6 5 11
2020 September 8 8 16
2020 August 8 11 19
2020 July 11 18 29
2020 June 6 4 10
2020 May 11 21 32
2020 April 13 11 24
2020 March 11 9 20
2020 February 12 14 26
2020 January 12 21 33
2019 December 7 13 20
2019 November 8 15 23
2019 October 4 11 15
2019 September 64 22 86
2019 August 8 8 16
2019 July 16 28 44
2019 June 2 21 23
2019 May 10 28 38
2019 April 10 36 46
2019 March 11 21 32
2019 February 14 9 23
2019 January 5 13 18
2018 December 7 12 19
2018 November 13 13 26
2018 October 9 11 20
2018 September 13 14 27
2018 May 4 0 4
2018 April 7 7 14
2018 March 2 2 4
2018 February 4 8 12
2018 January 3 11 14
2017 December 2 6 8
2017 November 7 5 12
2017 October 4 9 13
2017 September 4 9 13
2017 August 4 15 19
2017 July 2 8 10
2017 June 9 31 40
2017 May 4 8 12
2017 April 3 11 14
2017 March 4 23 27
2017 February 1 3 4
2017 January 2 8 10
2016 December 10 10 20
2016 November 11 9 20
2016 October 15 13 28
2016 September 10 10 20
2016 August 12 5 17
2016 July 5 9 14
2016 April 8 0 8
2016 March 1 0 1
2016 February 1 0 1
2015 December 2 0 2
2015 October 266 15 281
2015 September 271 14 285
2015 August 224 11 235
2015 July 296 20 316
2015 June 241 17 258
2015 May 289 25 314
2015 April 321 24 345
2015 March 386 36 422
2015 February 356 19 375
2015 January 324 29 353
2014 December 461 23 484
2014 November 415 20 435
2014 October 445 24 469
2014 September 348 17 365
2014 August 555 25 580
2014 July 1168 18 1186
2014 June 708 10 718
2014 May 331 8 339
2014 April 368 6 374
2014 March 342 13 355
2014 February 244 10 254
2014 January 207 9 216
2013 December 140 9 149
2013 November 74 7 81
2013 October 70 8 78
2013 September 71 15 86
2013 August 56 12 68
2013 July 74 21 95
2013 June 45 5 50
2013 May 52 5 57
2013 April 28 9 37
2013 March 15 1 16
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